Differences in Survival between Patients with Dementia with Lewy Bodies and Patients with Alzheimer's Disease - Measured from a Fixed Cognitive Level.
Stubendorff, Kajsa LU ; Hansson, Oskar LU
; Minthon, Lennart
LU
and Londos, Elisabet
LU
(2011)
In Dementia and Geriatric Cognitive Disorders
32(6).
p.408-416
- Abstract
- Introduction: The aim of this study was to compare survival in patients with Alzheimer's disease (AD) and patients with dementia with Lewy bodies (DLB). Since anamnestic and retrospective information about disease duration are unreliable variables, we measured survival from a fixed cognitive level. Methods: Survival time was measured from the reported disease onset, from the time of diagnosis, from Mini-Mental State Examination (MMSE) 20 ± 1, and from MMSE 17 ± 1. Results: Survival time was significantly shorter in the DLB group compared to the AD group both from the time of diagnosis and from the cognitive levels of 20 and 17 on the MMSE. There was no difference in survival when measured from the reported disease onset. Discussion: Our... (More)
- Introduction: The aim of this study was to compare survival in patients with Alzheimer's disease (AD) and patients with dementia with Lewy bodies (DLB). Since anamnestic and retrospective information about disease duration are unreliable variables, we measured survival from a fixed cognitive level. Methods: Survival time was measured from the reported disease onset, from the time of diagnosis, from Mini-Mental State Examination (MMSE) 20 ± 1, and from MMSE 17 ± 1. Results: Survival time was significantly shorter in the DLB group compared to the AD group both from the time of diagnosis and from the cognitive levels of 20 and 17 on the MMSE. There was no difference in survival when measured from the reported disease onset. Discussion: Our findings indicate that DLB patients have a more malignant clinical course. Our method of investigating survival in a cognitively homogenous population may gain scientific power. Reliable methods to predict survival and the clinical course are of great value for patients, caregivers, doctors, and society. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2367004
- author
- Stubendorff, Kajsa
LU
; Hansson, Oskar
LU
; Minthon, Lennart
LU
and Londos, Elisabet
LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Dementia and Geriatric Cognitive Disorders
- volume
- 32
- issue
- 6
- pages
- 408 - 416
- publisher
- Karger
- external identifiers
-
- wos:000300364500006
- pmid:22327504
- scopus:84856805730
- pmid:22327504
- ISSN
- 1420-8008
- DOI
- 10.1159/000335364
- language
- English
- LU publication?
- yes
- id
- 6b104443-e071-4c09-9ea2-1159b432525f (old id 2367004)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22327504?dopt=Abstract
- date added to LUP
- 2016-04-04 08:54:03
- date last changed
- 2022-03-15 08:56:33
@article{6b104443-e071-4c09-9ea2-1159b432525f,
abstract = {{Introduction: The aim of this study was to compare survival in patients with Alzheimer's disease (AD) and patients with dementia with Lewy bodies (DLB). Since anamnestic and retrospective information about disease duration are unreliable variables, we measured survival from a fixed cognitive level. Methods: Survival time was measured from the reported disease onset, from the time of diagnosis, from Mini-Mental State Examination (MMSE) 20 ± 1, and from MMSE 17 ± 1. Results: Survival time was significantly shorter in the DLB group compared to the AD group both from the time of diagnosis and from the cognitive levels of 20 and 17 on the MMSE. There was no difference in survival when measured from the reported disease onset. Discussion: Our findings indicate that DLB patients have a more malignant clinical course. Our method of investigating survival in a cognitively homogenous population may gain scientific power. Reliable methods to predict survival and the clinical course are of great value for patients, caregivers, doctors, and society.}},
author = {{Stubendorff, Kajsa and Hansson, Oskar and Minthon, Lennart and Londos, Elisabet}},
issn = {{1420-8008}},
language = {{eng}},
number = {{6}},
pages = {{408--416}},
publisher = {{Karger}},
series = {{Dementia and Geriatric Cognitive Disorders}},
title = {{Differences in Survival between Patients with Dementia with Lewy Bodies and Patients with Alzheimer's Disease - Measured from a Fixed Cognitive Level.}},
url = {{http://dx.doi.org/10.1159/000335364}},
doi = {{10.1159/000335364}},
volume = {{32}},
year = {{2011}},
}