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A personalized approach to the management of VWD

Phua, Chai W. and Berntorp, Erik LU (2019) In Transfusion and Apheresis Science 58(5). p.590-595
Abstract

The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Management of von Willebrand Disease, Personalization of von Willebrand Disease, Personalized approach to von Willebrand Disease, Treatment of von Willebrand Disease
in
Transfusion and Apheresis Science
volume
58
issue
5
pages
590 - 595
publisher
Elsevier
external identifiers
  • scopus:85071097870
  • pmid:31466808
ISSN
1473-0502
DOI
10.1016/j.transci.2019.08.009
language
English
LU publication?
yes
id
244a456b-068e-42fb-ab5c-7e75ddd1ec7b
date added to LUP
2019-09-05 16:15:58
date last changed
2020-01-13 15:18:04
@article{244a456b-068e-42fb-ab5c-7e75ddd1ec7b,
  abstract     = {<p>The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.</p>},
  author       = {Phua, Chai W. and Berntorp, Erik},
  issn         = {1473-0502},
  language     = {eng},
  month        = {08},
  number       = {5},
  pages        = {590--595},
  publisher    = {Elsevier},
  series       = {Transfusion and Apheresis Science},
  title        = {A personalized approach to the management of VWD},
  url          = {http://dx.doi.org/10.1016/j.transci.2019.08.009},
  doi          = {10.1016/j.transci.2019.08.009},
  volume       = {58},
  year         = {2019},
}