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Cancer among patients with diabetes, obesity and abnormal blood lipids: a population-based register study in Sweden.

Attner, Bo LU ; Landin-Olsson, Mona LU ; Lithman, Thor; Noreen, Dennis and Olsson, Håkan LU (2012) In Cancer Causes and Control 23(5). p.769-777
Abstract
OBJECTIVE:

To study how the incidence of cancer is related to diabetes, obesity or abnormal blood lipids.



METHODS:

Diagnosis of diabetes, obesity or abnormal blood lipids was studied 0-10 years prior to the diagnosis of cancer in 19,756 cases of cancer and in 147,324 controls matched regarding age, sex and domicile.



RESULTS:

Diabetes was significantly more common prior to diagnosis in patients with liver, pancreatic, colon and urinary tract/bladder cancer and in patients with breast cancer diagnosed with diabetes 0-4 years prior to the cancer diagnosis. A lower risk of diabetes was seen in patients with prostate carcinoma among individuals with diabetes diagnosed 5-10 years... (More)
OBJECTIVE:

To study how the incidence of cancer is related to diabetes, obesity or abnormal blood lipids.



METHODS:

Diagnosis of diabetes, obesity or abnormal blood lipids was studied 0-10 years prior to the diagnosis of cancer in 19,756 cases of cancer and in 147,324 controls matched regarding age, sex and domicile.



RESULTS:

Diabetes was significantly more common prior to diagnosis in patients with liver, pancreatic, colon and urinary tract/bladder cancer and in patients with breast cancer diagnosed with diabetes 0-4 years prior to the cancer diagnosis. A lower risk of diabetes was seen in patients with prostate carcinoma among individuals with diabetes diagnosed 5-10 years prior to the cancer diagnosis. The findings remained after adjusting for obesity and high blood lipids. Obesity was significantly more common in patients with endometrial, colon and kidney cancer and with breast cancer above the age of 60 years in those where obesity was diagnosed close to the diagnosis of cancer. High blood lipids were significantly more common in patients with ovarian cancer and less common in patients with breast cancer.



CONCLUSIONS:

The study confirms some previous findings concerning comorbidity and cancer and highlights some new ones. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cancer Causes and Control
volume
23
issue
5
pages
769 - 777
publisher
Springer
external identifiers
  • wos:000303418200012
  • pmid:22467266
  • scopus:84862583042
ISSN
1573-7225
DOI
10.1007/s10552-012-9946-5
language
English
LU publication?
yes
id
9256316a-156b-4167-b338-2af75dfa8380 (old id 2519993)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22467266?dopt=Abstract
date added to LUP
2012-05-04 12:45:36
date last changed
2017-07-23 04:52:34
@article{9256316a-156b-4167-b338-2af75dfa8380,
  abstract     = {OBJECTIVE:<br/><br>
To study how the incidence of cancer is related to diabetes, obesity or abnormal blood lipids.<br/><br>
<br/><br>
METHODS:<br/><br>
Diagnosis of diabetes, obesity or abnormal blood lipids was studied 0-10 years prior to the diagnosis of cancer in 19,756 cases of cancer and in 147,324 controls matched regarding age, sex and domicile.<br/><br>
<br/><br>
RESULTS:<br/><br>
Diabetes was significantly more common prior to diagnosis in patients with liver, pancreatic, colon and urinary tract/bladder cancer and in patients with breast cancer diagnosed with diabetes 0-4 years prior to the cancer diagnosis. A lower risk of diabetes was seen in patients with prostate carcinoma among individuals with diabetes diagnosed 5-10 years prior to the cancer diagnosis. The findings remained after adjusting for obesity and high blood lipids. Obesity was significantly more common in patients with endometrial, colon and kidney cancer and with breast cancer above the age of 60 years in those where obesity was diagnosed close to the diagnosis of cancer. High blood lipids were significantly more common in patients with ovarian cancer and less common in patients with breast cancer.<br/><br>
<br/><br>
CONCLUSIONS:<br/><br>
The study confirms some previous findings concerning comorbidity and cancer and highlights some new ones.},
  author       = {Attner, Bo and Landin-Olsson, Mona and Lithman, Thor and Noreen, Dennis and Olsson, Håkan},
  issn         = {1573-7225},
  language     = {eng},
  number       = {5},
  pages        = {769--777},
  publisher    = {Springer},
  series       = {Cancer Causes and Control},
  title        = {Cancer among patients with diabetes, obesity and abnormal blood lipids: a population-based register study in Sweden.},
  url          = {http://dx.doi.org/10.1007/s10552-012-9946-5},
  volume       = {23},
  year         = {2012},
}