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Does stage at diagnosis explain the difference in survival after breast cancer in Denmark and Sweden?

Jensen, AR; Garne, JP; Storm, HH; Engholm, G; Möller, Torgil LU and Overgaard, J (2004) In Acta Oncologica 43(8). p.719-726
Abstract
Breast cancer survival differs 9 percentage points between the neighbouring countries of Denmark and Sweden. The authors' aim was to analyse whether this was caused by early detection in Sweden. The extent of disease and outcome was compared in two population-based breast cancer cohorts in 1983-1989. Breast cancer management was decentralized in Denmark without mammography screening whereas treatment in Sweden was centralized and the population partly screened. Ten- and 15-year relative survival was 15% and 6% higher in Sweden (p <0.001) with corresponding differences in crude and disease-specific survival. Stage distribution was significantly more favourable in the Swedish cohort. In multivariate analysis age, tumour size, extent of... (More)
Breast cancer survival differs 9 percentage points between the neighbouring countries of Denmark and Sweden. The authors' aim was to analyse whether this was caused by early detection in Sweden. The extent of disease and outcome was compared in two population-based breast cancer cohorts in 1983-1989. Breast cancer management was decentralized in Denmark without mammography screening whereas treatment in Sweden was centralized and the population partly screened. Ten- and 15-year relative survival was 15% and 6% higher in Sweden (p <0.001) with corresponding differences in crude and disease-specific survival. Stage distribution was significantly more favourable in the Swedish cohort. In multivariate analysis age, tumour size, extent of axillary surgery, and spread affected survival; however, the impact of region persisted (p <0.001). Reanalysis without screening-detected patients only slightly affected the impact of region. It was concluded that early detection had significant impact on survival but other regional differences might be of importance. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Oncologica
volume
43
issue
8
pages
719 - 726
publisher
Taylor & Francis
external identifiers
  • wos:000225945700004
  • pmid:15764216
  • scopus:11244309886
ISSN
1651-226X
DOI
10.1080/02841860410002789
language
English
LU publication?
yes
id
96f660a9-df87-4d30-b87c-c079f7fdd902 (old id 259079)
date added to LUP
2007-10-23 11:53:31
date last changed
2017-11-05 04:27:09
@article{96f660a9-df87-4d30-b87c-c079f7fdd902,
  abstract     = {Breast cancer survival differs 9 percentage points between the neighbouring countries of Denmark and Sweden. The authors' aim was to analyse whether this was caused by early detection in Sweden. The extent of disease and outcome was compared in two population-based breast cancer cohorts in 1983-1989. Breast cancer management was decentralized in Denmark without mammography screening whereas treatment in Sweden was centralized and the population partly screened. Ten- and 15-year relative survival was 15% and 6% higher in Sweden (p &lt;0.001) with corresponding differences in crude and disease-specific survival. Stage distribution was significantly more favourable in the Swedish cohort. In multivariate analysis age, tumour size, extent of axillary surgery, and spread affected survival; however, the impact of region persisted (p &lt;0.001). Reanalysis without screening-detected patients only slightly affected the impact of region. It was concluded that early detection had significant impact on survival but other regional differences might be of importance.},
  author       = {Jensen, AR and Garne, JP and Storm, HH and Engholm, G and Möller, Torgil and Overgaard, J},
  issn         = {1651-226X},
  language     = {eng},
  number       = {8},
  pages        = {719--726},
  publisher    = {Taylor & Francis},
  series       = {Acta Oncologica},
  title        = {Does stage at diagnosis explain the difference in survival after breast cancer in Denmark and Sweden?},
  url          = {http://dx.doi.org/10.1080/02841860410002789},
  volume       = {43},
  year         = {2004},
}