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Determination of the biodistribution and dosimetry of (123)I-FP-CIT in male patients with suspected Parkinsonism or Lewy body dementia using planar and combined planar and SPECT/CT imaging.

Sydoff, Marie LU ; Lizana, Helena ; Mattsson, Sören LU ; Stabin, Michael G and Leide Svegborn, Sigrid LU (2013) In Applied Radiation and Isotopes 82. p.300-307
Abstract
In this study, (123)I-FP-CIT biodistribution and dosimetry was determined in 10 adult male patients using planar gamma camera imaging alone or in combination with single photon emission computed tomography /X-ray computed tomography (SPECT/CT) imaging. Dosimetric assessment using planar plus SPECT/CT imaging resulted in significantly different estimates of organ-absorbed doses compared to estimates based on planar imaging alone. We conclude that the use of complementary SPECT/CT measurements in biodistribution studies is valuable for determining the organ doses more accurately.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Applied Radiation and Isotopes
volume
82
pages
300 - 307
publisher
Elsevier
external identifiers
  • wos:000328804000046
  • pmid:24135637
  • scopus:84885929322
ISSN
0969-8043
DOI
10.1016/j.apradiso.2013.09.006
language
English
LU publication?
yes
id
2607169e-8388-4453-a096-a0a21ea839a6 (old id 4143196)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24135637?dopt=Abstract
date added to LUP
2016-04-01 10:50:25
date last changed
2022-01-26 02:55:25
@article{2607169e-8388-4453-a096-a0a21ea839a6,
  abstract     = {{In this study, (123)I-FP-CIT biodistribution and dosimetry was determined in 10 adult male patients using planar gamma camera imaging alone or in combination with single photon emission computed tomography /X-ray computed tomography (SPECT/CT) imaging. Dosimetric assessment using planar plus SPECT/CT imaging resulted in significantly different estimates of organ-absorbed doses compared to estimates based on planar imaging alone. We conclude that the use of complementary SPECT/CT measurements in biodistribution studies is valuable for determining the organ doses more accurately.}},
  author       = {{Sydoff, Marie and Lizana, Helena and Mattsson, Sören and Stabin, Michael G and Leide Svegborn, Sigrid}},
  issn         = {{0969-8043}},
  language     = {{eng}},
  pages        = {{300--307}},
  publisher    = {{Elsevier}},
  series       = {{Applied Radiation and Isotopes}},
  title        = {{Determination of the biodistribution and dosimetry of (123)I-FP-CIT in male patients with suspected Parkinsonism or Lewy body dementia using planar and combined planar and SPECT/CT imaging.}},
  url          = {{http://dx.doi.org/10.1016/j.apradiso.2013.09.006}},
  doi          = {{10.1016/j.apradiso.2013.09.006}},
  volume       = {{82}},
  year         = {{2013}},
}