Advanced

Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy

Jensen, PS; Bak, J; Ladefoged, S; Andersson-Engels, Stefan LU and Friis-Hansen, L (2004) In Journal of Biomedical Optics 9(3). p.553-557
Abstract
The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a period of 1 month. The calibration was robust when faced with adjustment of reference cell intensity and did not require a daily measured reference spectrum. The root-mean-square error of prediction of urea was 0.4 mM based on a two-factor partial least-squares regression model. (C) 2004 Society of Photo-Optical Instrumentation Engineers.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
online, dialysis, spectroscopy, dual-beam, near-infrared, urea
in
Journal of Biomedical Optics
volume
9
issue
3
pages
553 - 557
publisher
Published by SPIE--the International Society for Optical Engineering in cooperation with International Biomedical Optics Society
external identifiers
  • wos:000221304400016
  • scopus:2942729885
ISSN
1083-3668
DOI
10.1117/1.1689337
language
English
LU publication?
yes
id
851e092f-9713-4745-af3f-9f5cb3679110 (old id 279400)
date added to LUP
2007-10-23 12:25:10
date last changed
2017-02-12 03:33:45
@article{851e092f-9713-4745-af3f-9f5cb3679110,
  abstract     = {The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a period of 1 month. The calibration was robust when faced with adjustment of reference cell intensity and did not require a daily measured reference spectrum. The root-mean-square error of prediction of urea was 0.4 mM based on a two-factor partial least-squares regression model. (C) 2004 Society of Photo-Optical Instrumentation Engineers.},
  author       = {Jensen, PS and Bak, J and Ladefoged, S and Andersson-Engels, Stefan and Friis-Hansen, L},
  issn         = {1083-3668},
  keyword      = {online,dialysis,spectroscopy,dual-beam,near-infrared,urea},
  language     = {eng},
  number       = {3},
  pages        = {553--557},
  publisher    = {Published by SPIE--the International Society for Optical Engineering in cooperation with International Biomedical Optics Society},
  series       = {Journal of Biomedical Optics},
  title        = {Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy},
  url          = {http://dx.doi.org/10.1117/1.1689337},
  volume       = {9},
  year         = {2004},
}