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Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy

Jensen, PS ; Bak, J ; Ladefoged, S ; Andersson-Engels, Stefan LU and Friis-Hansen, L (2004) In Journal of Biomedical Optics 9(3). p.553-557
Abstract
The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a period of 1 month. The calibration was robust when faced with adjustment of reference cell intensity and did not require a daily measured reference spectrum. The root-mean-square error of prediction of urea was 0.4 mM based on a two-factor partial least-squares regression model. (C) 2004 Society of Photo-Optical Instrumentation Engineers.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
online, dialysis, spectroscopy, dual-beam, near-infrared, urea
in
Journal of Biomedical Optics
volume
9
issue
3
pages
553 - 557
publisher
SPIE
external identifiers
  • wos:000221304400016
  • scopus:2942729885
ISSN
1083-3668
DOI
10.1117/1.1689337
language
English
LU publication?
yes
id
851e092f-9713-4745-af3f-9f5cb3679110 (old id 279400)
date added to LUP
2016-04-01 12:12:59
date last changed
2022-01-27 00:33:00
@article{851e092f-9713-4745-af3f-9f5cb3679110,
  abstract     = {{The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a period of 1 month. The calibration was robust when faced with adjustment of reference cell intensity and did not require a daily measured reference spectrum. The root-mean-square error of prediction of urea was 0.4 mM based on a two-factor partial least-squares regression model. (C) 2004 Society of Photo-Optical Instrumentation Engineers.}},
  author       = {{Jensen, PS and Bak, J and Ladefoged, S and Andersson-Engels, Stefan and Friis-Hansen, L}},
  issn         = {{1083-3668}},
  keywords     = {{online; dialysis; spectroscopy; dual-beam; near-infrared; urea}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{553--557}},
  publisher    = {{SPIE}},
  series       = {{Journal of Biomedical Optics}},
  title        = {{Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy}},
  url          = {{https://lup.lub.lu.se/search/files/2830778/2370288.pdf}},
  doi          = {{10.1117/1.1689337}},
  volume       = {{9}},
  year         = {{2004}},
}