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New directions of miniaturization within the proteomics research area

Marko-Varga, György LU ; Nilsson, Johan LU and Laurell, Thomas LU (2003) In Electrophoresis 24(21). p.3521-3532
Abstract
An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
proteomics, miniaturization, protein expression profiling, review
in
Electrophoresis
volume
24
issue
21
pages
3521 - 3532
publisher
John Wiley & Sons
external identifiers
  • wos:000186858700002
  • pmid:14613179
  • scopus:0347764579
ISSN
0173-0835
DOI
language
English
LU publication?
yes
id
ced33133-61e6-4a21-85dd-dd8475cb61f5 (old id 294619)
date added to LUP
2007-09-18 07:29:08
date last changed
2018-05-29 11:30:13
@article{ced33133-61e6-4a21-85dd-dd8475cb61f5,
  abstract     = {An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.},
  author       = {Marko-Varga, György and Nilsson, Johan and Laurell, Thomas},
  issn         = {0173-0835},
  keyword      = {proteomics,miniaturization,protein expression profiling,review},
  language     = {eng},
  number       = {21},
  pages        = {3521--3532},
  publisher    = {John Wiley & Sons},
  series       = {Electrophoresis},
  title        = {New directions of miniaturization within the proteomics research area},
  url          = {http://dx.doi.org/},
  volume       = {24},
  year         = {2003},
}