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A sol-gel integrated dual-readout microarray platform for quantification and identification of prostate-specific antigen

Lee, S. W. LU ; Lee, J. H.; Kwon, H. G.; Laurell, T. LU ; Jeong, O. C. and Kim, S. (2018) 28th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2017 2018-January.
Abstract

Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multianalyte sensing and high-throughput analysis of protein-protein and protein-ligand interactions. This technique provides high-sensitivity analysis of biomarkers, as well as molecular profiling, and is thus used in the fields of life science, medicine and proteomics [1]. In clinical application, the high sensitive biomarker analysis enables early... (More)

Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multianalyte sensing and high-throughput analysis of protein-protein and protein-ligand interactions. This technique provides high-sensitivity analysis of biomarkers, as well as molecular profiling, and is thus used in the fields of life science, medicine and proteomics [1]. In clinical application, the high sensitive biomarker analysis enables early diagnosis, and prediction of prognosis and the response to treatment [2,3].

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
MHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science
volume
2018-January
pages
2 pages
publisher
Institute of Electrical and Electronics Engineers Inc.
conference name
28th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2017
conference location
Nagoya, Japan
conference dates
2017-12-03 - 2017-12-06
external identifiers
  • scopus:85050544541
ISBN
9781538633144
DOI
10.1109/MHS.2017.8305253
language
English
LU publication?
yes
id
2d7c217e-c90f-42ee-bc4b-ee0266fded8a
date added to LUP
2018-09-18 12:04:54
date last changed
2019-01-06 14:05:18
@inproceedings{2d7c217e-c90f-42ee-bc4b-ee0266fded8a,
  abstract     = {<p>Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multianalyte sensing and high-throughput analysis of protein-protein and protein-ligand interactions. This technique provides high-sensitivity analysis of biomarkers, as well as molecular profiling, and is thus used in the fields of life science, medicine and proteomics [1]. In clinical application, the high sensitive biomarker analysis enables early diagnosis, and prediction of prognosis and the response to treatment [2,3].</p>},
  author       = {Lee, S. W. and Lee, J. H. and Kwon, H. G. and Laurell, T. and Jeong, O. C. and Kim, S.},
  isbn         = {9781538633144},
  language     = {eng},
  location     = {Nagoya, Japan},
  month        = {02},
  pages        = {2},
  publisher    = {Institute of Electrical and Electronics Engineers Inc.},
  title        = {A sol-gel integrated dual-readout microarray platform for quantification and identification of prostate-specific antigen},
  url          = {http://dx.doi.org/10.1109/MHS.2017.8305253},
  volume       = {2018-January},
  year         = {2018},
}