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An automated method for the detection of pulmonary embolism in V/Q-scans

Frigyesi, Attila LU (2003) In Medical Image Analysis 7(3). p.341-349
Abstract
In this paper, a fully automatic method for the diagnosis of pulmonary embolism (PE) from V/Q-scans is presented. Image analysis is applied to the ventilation and the perfusion images obtained in the V/Q-scan. The difference of the ventilation and the perfusion is calculated after transformation and hot-spot reduction of the images. From this difference image the integral of the underperfused areas are used as features. With the aid of these features a simple test for PE is devised. The method is evaluated on two sets of patients. One set comprises 102 patients who have undergone both V/Q-scanning and angiography. The performance given as the area under the Receiver Operating Characteristic (ROC) curve is 0.85. Another set is made up by... (More)
In this paper, a fully automatic method for the diagnosis of pulmonary embolism (PE) from V/Q-scans is presented. Image analysis is applied to the ventilation and the perfusion images obtained in the V/Q-scan. The difference of the ventilation and the perfusion is calculated after transformation and hot-spot reduction of the images. From this difference image the integral of the underperfused areas are used as features. With the aid of these features a simple test for PE is devised. The method is evaluated on two sets of patients. One set comprises 102 patients who have undergone both V/Q-scanning and angiography. The performance given as the area under the Receiver Operating Characteristic (ROC) curve is 0.85. Another set is made up by the 507 consecutive patients examined with V/Q-scanning at Lund University Hospital in Sweden. In this case, the reference was the consensus opinion of two radiologists, the ROC-area is 0.67. A fully automatic and reasonably robust expert system is developed to aid the radiologist in the interpretation of V/Q-scans for PE. (C) 2003 Elsevier B.V. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
automated method, pulmonary embolism, V/Q-scans
in
Medical Image Analysis
volume
7
issue
3
pages
341 - 349
publisher
Elsevier
external identifiers
  • pmid:12946472
  • wos:000185435300009
  • scopus:0042827521
ISSN
1361-8415
DOI
10.1016/S1361-8415(03)00030-6
language
English
LU publication?
yes
id
25545245-9559-4430-a4dd-09f7395c1cbc (old id 300041)
date added to LUP
2007-08-02 15:32:28
date last changed
2018-01-07 05:50:21
@article{25545245-9559-4430-a4dd-09f7395c1cbc,
  abstract     = {In this paper, a fully automatic method for the diagnosis of pulmonary embolism (PE) from V/Q-scans is presented. Image analysis is applied to the ventilation and the perfusion images obtained in the V/Q-scan. The difference of the ventilation and the perfusion is calculated after transformation and hot-spot reduction of the images. From this difference image the integral of the underperfused areas are used as features. With the aid of these features a simple test for PE is devised. The method is evaluated on two sets of patients. One set comprises 102 patients who have undergone both V/Q-scanning and angiography. The performance given as the area under the Receiver Operating Characteristic (ROC) curve is 0.85. Another set is made up by the 507 consecutive patients examined with V/Q-scanning at Lund University Hospital in Sweden. In this case, the reference was the consensus opinion of two radiologists, the ROC-area is 0.67. A fully automatic and reasonably robust expert system is developed to aid the radiologist in the interpretation of V/Q-scans for PE. (C) 2003 Elsevier B.V. All rights reserved.},
  author       = {Frigyesi, Attila},
  issn         = {1361-8415},
  keyword      = {automated method,pulmonary embolism,V/Q-scans},
  language     = {eng},
  number       = {3},
  pages        = {341--349},
  publisher    = {Elsevier},
  series       = {Medical Image Analysis},
  title        = {An automated method for the detection of pulmonary embolism in V/Q-scans},
  url          = {http://dx.doi.org/10.1016/S1361-8415(03)00030-6},
  volume       = {7},
  year         = {2003},
}