Diagnostic delay and prognosis in invasive bladder cancer
(2003) In Scandinavian Journal of Urology and Nephrology 37(5). p.396-400- Abstract
- Objectives: To study diagnostic delay in invasive bladder cancer in a population-based material with long-term follow-up, and to evaluate whether delay in diagnosis affects the risk of bladder cancer death. Material and Methods: In a previous study, 177 patients with invasive bladder cancer (T1-T4) diagnosed in 1988 were investigated with regard to diagnostic delay. A review of all available clinical records was performed. In the present study, causes of death for these patients were registered over a 12-year follow-up period, and the impact of diagnostic delay on bladder cancer death was studied by means of survival analysis. Results: The median diagnostic delay in the material was 144 days. When the patients were stratified into groups... (More)
- Objectives: To study diagnostic delay in invasive bladder cancer in a population-based material with long-term follow-up, and to evaluate whether delay in diagnosis affects the risk of bladder cancer death. Material and Methods: In a previous study, 177 patients with invasive bladder cancer (T1-T4) diagnosed in 1988 were investigated with regard to diagnostic delay. A review of all available clinical records was performed. In the present study, causes of death for these patients were registered over a 12-year follow-up period, and the impact of diagnostic delay on bladder cancer death was studied by means of survival analysis. Results: The median diagnostic delay in the material was 144 days. When the patients were stratified into groups with diagnostic delays of 0-3, 3-6, 6-12 and >12 months, those with T1 tumours in the two groups with a diagnostic delay of <6 months showed a trend towards a decreased risk of bladder cancer death. In contrast, in patients with muscle-invasive disease, a significantly increased risk of bladder cancer death was noted for those with a diagnostic delay of <6 months. Conclusion: A trend towards better prognosis was found for patients with T1 tumours with a shorter diagnostic delay. The poor prognosis of patients with muscle-invasive disease and a short diagnostic delay suggests aggressive behaviour of the tumour and may explain the worse prognosis in these patients. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/296387
- author
- Liedberg, Fredrik LU ; Anderson, Harald LU ; Mansson, A and Månsson, Wiking LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bladder cancer, diagnostic delay, prognosis
- in
- Scandinavian Journal of Urology and Nephrology
- volume
- 37
- issue
- 5
- pages
- 396 - 400
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000186295000006
- pmid:14594688
- scopus:0345304834
- pmid:14594688
- ISSN
- 0036-5599
- DOI
- 10.1080/00365590310006246
- language
- English
- LU publication?
- yes
- id
- 30f714b0-c444-4f7e-a227-440ad0d9c8ae (old id 296387)
- date added to LUP
- 2016-04-01 16:36:39
- date last changed
- 2022-01-28 20:55:50
@article{30f714b0-c444-4f7e-a227-440ad0d9c8ae,
abstract = {{Objectives: To study diagnostic delay in invasive bladder cancer in a population-based material with long-term follow-up, and to evaluate whether delay in diagnosis affects the risk of bladder cancer death. Material and Methods: In a previous study, 177 patients with invasive bladder cancer (T1-T4) diagnosed in 1988 were investigated with regard to diagnostic delay. A review of all available clinical records was performed. In the present study, causes of death for these patients were registered over a 12-year follow-up period, and the impact of diagnostic delay on bladder cancer death was studied by means of survival analysis. Results: The median diagnostic delay in the material was 144 days. When the patients were stratified into groups with diagnostic delays of 0-3, 3-6, 6-12 and >12 months, those with T1 tumours in the two groups with a diagnostic delay of <6 months showed a trend towards a decreased risk of bladder cancer death. In contrast, in patients with muscle-invasive disease, a significantly increased risk of bladder cancer death was noted for those with a diagnostic delay of <6 months. Conclusion: A trend towards better prognosis was found for patients with T1 tumours with a shorter diagnostic delay. The poor prognosis of patients with muscle-invasive disease and a short diagnostic delay suggests aggressive behaviour of the tumour and may explain the worse prognosis in these patients.}},
author = {{Liedberg, Fredrik and Anderson, Harald and Mansson, A and Månsson, Wiking}},
issn = {{0036-5599}},
keywords = {{bladder cancer; diagnostic delay; prognosis}},
language = {{eng}},
number = {{5}},
pages = {{396--400}},
publisher = {{Taylor & Francis}},
series = {{Scandinavian Journal of Urology and Nephrology}},
title = {{Diagnostic delay and prognosis in invasive bladder cancer}},
url = {{http://dx.doi.org/10.1080/00365590310006246}},
doi = {{10.1080/00365590310006246}},
volume = {{37}},
year = {{2003}},
}