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Time Trends and Sex Differences in the Invasive Treatment of Infrainguinal Intermittent Claudication in Sweden During 2009 – 2022 : Results From the Swedish Vascular Registry (Swedvasc)

Gunnarsson, Thordur S. LU ; Bergman, Stefan ; Pärsson, Håkan ; Gottsäter, Anders LU and Lindgren, Hans LU (2025) In European Journal of Vascular and Endovascular Surgery 70(2). p.247-255
Abstract

Objective: This study aimed to report changes in the annual incidence of invasive treatment, changes in invasive treatment modalities, and sex differences in patients treated for intermittent claudication (IC) due to infrainguinal lesions in Sweden between 2009 and 2022. Methods: Data were collected from the Swedish Vascular Registry (Swedvasc), including all registrations of invasive treatment for infrainguinal IC in Sweden between 2009 and 2022. Results: The annual incidence of invasive treatments showed no statistically significant change between 2009 and 2022 (p = .21). The proportion of open surgery decreased from 38.1% in 2009 to 23.4% in 2022 (p < .001). Endovascular and hybrid interventions increased from 56.9% to 69.7% (p... (More)

Objective: This study aimed to report changes in the annual incidence of invasive treatment, changes in invasive treatment modalities, and sex differences in patients treated for intermittent claudication (IC) due to infrainguinal lesions in Sweden between 2009 and 2022. Methods: Data were collected from the Swedish Vascular Registry (Swedvasc), including all registrations of invasive treatment for infrainguinal IC in Sweden between 2009 and 2022. Results: The annual incidence of invasive treatments showed no statistically significant change between 2009 and 2022 (p = .21). The proportion of open surgery decreased from 38.1% in 2009 to 23.4% in 2022 (p < .001). Endovascular and hybrid interventions increased from 56.9% to 69.7% (p < .001) and from 4.8% to 7.0% (p < .001), respectively, between 2009 and 2022 according to time trend analysis. The decrease in open surgery was due to a reduction in bypass surgery from 18.8% in 2009 to 4.0% in 2022 (p < .001). The proportion of common femoral artery thrombo-endarterectomy remained unchanged (p = .24). During the study period, 42.7% of invasive treatments were performed in women. Open surgery was more frequently performed in men than women (32.5% vs. 24.0%; p < .001). However, endovascular intervention was statistically significantly more frequently performed in women than men (70.7% vs. 61.6%; p < .001). Conclusion: The annual incidence of invasive treatment for infrainguinal IC in Sweden was unchanged between 2009 and 2022. The proportion of endovascular interventions increased and accounted for 70% of invasive treatments in 2022, whereas bypass surgery decreased by 79%. Women were more often treated with endovascular intervention than men.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Endovascular, Infrainguinal, Intermittent claudication, Peripheral arterial disease, Swedvasc, Vascular surgery
in
European Journal of Vascular and Endovascular Surgery
volume
70
issue
2
pages
9 pages
publisher
Elsevier
external identifiers
  • pmid:40058521
  • scopus:105001870744
ISSN
1078-5884
DOI
10.1016/j.ejvs.2025.03.002
language
English
LU publication?
yes
id
3111fafd-d9c5-4fd0-8145-cfbf7106ae4e
date added to LUP
2025-09-02 13:45:55
date last changed
2025-09-30 16:16:44
@article{3111fafd-d9c5-4fd0-8145-cfbf7106ae4e,
  abstract     = {{<p>Objective: This study aimed to report changes in the annual incidence of invasive treatment, changes in invasive treatment modalities, and sex differences in patients treated for intermittent claudication (IC) due to infrainguinal lesions in Sweden between 2009 and 2022. Methods: Data were collected from the Swedish Vascular Registry (Swedvasc), including all registrations of invasive treatment for infrainguinal IC in Sweden between 2009 and 2022. Results: The annual incidence of invasive treatments showed no statistically significant change between 2009 and 2022 (p = .21). The proportion of open surgery decreased from 38.1% in 2009 to 23.4% in 2022 (p &lt; .001). Endovascular and hybrid interventions increased from 56.9% to 69.7% (p &lt; .001) and from 4.8% to 7.0% (p &lt; .001), respectively, between 2009 and 2022 according to time trend analysis. The decrease in open surgery was due to a reduction in bypass surgery from 18.8% in 2009 to 4.0% in 2022 (p &lt; .001). The proportion of common femoral artery thrombo-endarterectomy remained unchanged (p = .24). During the study period, 42.7% of invasive treatments were performed in women. Open surgery was more frequently performed in men than women (32.5% vs. 24.0%; p &lt; .001). However, endovascular intervention was statistically significantly more frequently performed in women than men (70.7% vs. 61.6%; p &lt; .001). Conclusion: The annual incidence of invasive treatment for infrainguinal IC in Sweden was unchanged between 2009 and 2022. The proportion of endovascular interventions increased and accounted for 70% of invasive treatments in 2022, whereas bypass surgery decreased by 79%. Women were more often treated with endovascular intervention than men.</p>}},
  author       = {{Gunnarsson, Thordur S. and Bergman, Stefan and Pärsson, Håkan and Gottsäter, Anders and Lindgren, Hans}},
  issn         = {{1078-5884}},
  keywords     = {{Endovascular; Infrainguinal; Intermittent claudication; Peripheral arterial disease; Swedvasc; Vascular surgery}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{247--255}},
  publisher    = {{Elsevier}},
  series       = {{European Journal of Vascular and Endovascular Surgery}},
  title        = {{Time Trends and Sex Differences in the Invasive Treatment of Infrainguinal Intermittent Claudication in Sweden During 2009 – 2022 : Results From the Swedish Vascular Registry (Swedvasc)}},
  url          = {{http://dx.doi.org/10.1016/j.ejvs.2025.03.002}},
  doi          = {{10.1016/j.ejvs.2025.03.002}},
  volume       = {{70}},
  year         = {{2025}},
}