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Immunoglobulins, growth factors and growth hormone in bovine colostrum and the effects of processing

Elfstrand, Lidia LU ; Lindmark Månsson, Helena LU ; Paulsson, Marie LU ; Nyberg, L and Åkesson, Björn LU (2002) In International Dairy Journal 12(11). p.879-887
Abstract
In colostrum collected 0-80 h postpartum the contents of immunoglobulins (Igs), transforming growth factor beta-2 (TGF-beta2), insulin-like growth factor-1 (IGF-1) and growth hormone (GH) were analysed. Colostrum initially contained 90 mg mL(-1) IgG1, 2.8 mg mL(-1) IgG2, 1.6 mg mL(-1) IgA, 4.5 mg mL(-1) IgM, and these concentrations declined by 92%, 87%, 93% and 84%, respectively, in the samples collected later. Of the growth factors, colostrum initially contained 289-310 ng mL(-1) TGF-beta2 and the concentration diminished to 66 ng mL(-1). The content of IGF-1 and GH postpartum decreased from 870 to 150 ng mL(-1), and from 0.17 to < 0.03 ng mL(-1), respectively. Heat treatment and freeze-drying of colostral whey decreased the content... (More)
In colostrum collected 0-80 h postpartum the contents of immunoglobulins (Igs), transforming growth factor beta-2 (TGF-beta2), insulin-like growth factor-1 (IGF-1) and growth hormone (GH) were analysed. Colostrum initially contained 90 mg mL(-1) IgG1, 2.8 mg mL(-1) IgG2, 1.6 mg mL(-1) IgA, 4.5 mg mL(-1) IgM, and these concentrations declined by 92%, 87%, 93% and 84%, respectively, in the samples collected later. Of the growth factors, colostrum initially contained 289-310 ng mL(-1) TGF-beta2 and the concentration diminished to 66 ng mL(-1). The content of IGF-1 and GH postpartum decreased from 870 to 150 ng mL(-1), and from 0.17 to < 0.03 ng mL(-1), respectively. Heat treatment and freeze-drying of colostral whey decreased the content of Igs to 75%, while the contents of IGF-1 and TGF-beta2 were unaffected. A similar processing, including filtration steps reduced also the IGF-1 and TGF-beta2 by 25%. IgM seems to be the most sensitive of the Igs to processing. (C) 2002 Elsevier Science Ltd. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
immunological techniques, processing effects, growth hormone, growth factors, bovine colostrum, immunoglobulins
in
International Dairy Journal
volume
12
issue
11
pages
879 - 887
publisher
Elsevier
external identifiers
  • wos:000180105500002
  • scopus:0036913607
ISSN
0958-6946
DOI
10.1016/S0958-6946(02)00089-4
language
English
LU publication?
yes
id
3f70696d-5ac7-48a6-ba01-364e8ea0a314 (old id 320702)
date added to LUP
2007-08-16 16:17:32
date last changed
2017-11-05 04:30:06
@article{3f70696d-5ac7-48a6-ba01-364e8ea0a314,
  abstract     = {In colostrum collected 0-80 h postpartum the contents of immunoglobulins (Igs), transforming growth factor beta-2 (TGF-beta2), insulin-like growth factor-1 (IGF-1) and growth hormone (GH) were analysed. Colostrum initially contained 90 mg mL(-1) IgG1, 2.8 mg mL(-1) IgG2, 1.6 mg mL(-1) IgA, 4.5 mg mL(-1) IgM, and these concentrations declined by 92%, 87%, 93% and 84%, respectively, in the samples collected later. Of the growth factors, colostrum initially contained 289-310 ng mL(-1) TGF-beta2 and the concentration diminished to 66 ng mL(-1). The content of IGF-1 and GH postpartum decreased from 870 to 150 ng mL(-1), and from 0.17 to &lt; 0.03 ng mL(-1), respectively. Heat treatment and freeze-drying of colostral whey decreased the content of Igs to 75%, while the contents of IGF-1 and TGF-beta2 were unaffected. A similar processing, including filtration steps reduced also the IGF-1 and TGF-beta2 by 25%. IgM seems to be the most sensitive of the Igs to processing. (C) 2002 Elsevier Science Ltd. All rights reserved.},
  author       = {Elfstrand, Lidia and Lindmark Månsson, Helena and Paulsson, Marie and Nyberg, L and Åkesson, Björn},
  issn         = {0958-6946},
  keyword      = {immunological techniques,processing effects,growth hormone,growth factors,bovine colostrum,immunoglobulins},
  language     = {eng},
  number       = {11},
  pages        = {879--887},
  publisher    = {Elsevier},
  series       = {International Dairy Journal},
  title        = {Immunoglobulins, growth factors and growth hormone in bovine colostrum and the effects of processing},
  url          = {http://dx.doi.org/10.1016/S0958-6946(02)00089-4},
  volume       = {12},
  year         = {2002},
}