Regulation of apical growth and hyphal branching in Streptomyces
(2012) In Current Opinion in Microbiology 15(6). p.737-743- Abstract
- The filamentous bacteria Streptomyces grow by tip extension and through the initiation of new branches, and this apical growth is directed by a polarisome-like complex involving the essential polarity protein DivIVA. New branch sites must be marked de novo and, until recently, there was no understanding of how these new sites are selected. Equally, hyphal branching patterns are affected by environmental conditions, but there was no insight into how polar growth and hyphal branching might be regulated in response to external or internal cues. This review focuses on recent discoveries that reveal the principal mechanism of branch site selection in Streptomyces, and the first mechanism to be identified that regulates polarisome behaviour to... (More)
- The filamentous bacteria Streptomyces grow by tip extension and through the initiation of new branches, and this apical growth is directed by a polarisome-like complex involving the essential polarity protein DivIVA. New branch sites must be marked de novo and, until recently, there was no understanding of how these new sites are selected. Equally, hyphal branching patterns are affected by environmental conditions, but there was no insight into how polar growth and hyphal branching might be regulated in response to external or internal cues. This review focuses on recent discoveries that reveal the principal mechanism of branch site selection in Streptomyces, and the first mechanism to be identified that regulates polarisome behaviour to modulate polar growth and hyphal branching. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3218936
- author
- Flärdh, Klas LU ; Richards, David M ; Hempel, Antje M ; Howard, Martin and Buttner, Mark J
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Current Opinion in Microbiology
- volume
- 15
- issue
- 6
- pages
- 737 - 743
- publisher
- Elsevier
- external identifiers
-
- wos:000313612200016
- pmid:23153774
- scopus:84872277207
- pmid:23153774
- ISSN
- 1879-0364
- DOI
- 10.1016/j.mib.2012.10.012
- language
- English
- LU publication?
- yes
- id
- 2c69519c-8ad8-4857-af74-88591cbbb8bd (old id 3218936)
- date added to LUP
- 2016-04-01 11:00:53
- date last changed
- 2022-04-12 19:42:22
@article{2c69519c-8ad8-4857-af74-88591cbbb8bd,
abstract = {{The filamentous bacteria Streptomyces grow by tip extension and through the initiation of new branches, and this apical growth is directed by a polarisome-like complex involving the essential polarity protein DivIVA. New branch sites must be marked de novo and, until recently, there was no understanding of how these new sites are selected. Equally, hyphal branching patterns are affected by environmental conditions, but there was no insight into how polar growth and hyphal branching might be regulated in response to external or internal cues. This review focuses on recent discoveries that reveal the principal mechanism of branch site selection in Streptomyces, and the first mechanism to be identified that regulates polarisome behaviour to modulate polar growth and hyphal branching.}},
author = {{Flärdh, Klas and Richards, David M and Hempel, Antje M and Howard, Martin and Buttner, Mark J}},
issn = {{1879-0364}},
language = {{eng}},
number = {{6}},
pages = {{737--743}},
publisher = {{Elsevier}},
series = {{Current Opinion in Microbiology}},
title = {{Regulation of apical growth and hyphal branching in Streptomyces}},
url = {{http://dx.doi.org/10.1016/j.mib.2012.10.012}},
doi = {{10.1016/j.mib.2012.10.012}},
volume = {{15}},
year = {{2012}},
}