Value of conventional, and diffusion- and perfusion weighted MRI in the management of patients with unclear cerebral pathology, admitted to the intensive care unit
Sundgren, Pia LU
; Reinstrup, Peter
LU
; Romner, Bertil
LU
; Holtås, Stig
LU
and Maly, Pavel
LU
(2002)
In Neuroradiology
44(8).
p.674-680
- Abstract
- The aim of our retrospective study was to determine the extent to which diffusion- and perfusion- weighted MRI combined with conventional MRI could be helpful in the evaluation of intensive care unit (ICU) patients who have unknown or unclear cerebral pathology underlying a serious clinical condition. Twenty-one ICU patients with disparity between the findings on brain CT scan and their clinical status were studied. All patients underwent conventional MR and diffusion-weighted imaging and 14 also had MR perfusion studies. Abnormalities were present on diffusion-weighted imaging of 17 of the 21 patients and on perfusion-weighted studies of 7 of 14 patients. The MRI results changed the preliminary/working diagnosis in six patients. In eight... (More)
- The aim of our retrospective study was to determine the extent to which diffusion- and perfusion- weighted MRI combined with conventional MRI could be helpful in the evaluation of intensive care unit (ICU) patients who have unknown or unclear cerebral pathology underlying a serious clinical condition. Twenty-one ICU patients with disparity between the findings on brain CT scan and their clinical status were studied. All patients underwent conventional MR and diffusion-weighted imaging and 14 also had MR perfusion studies. Abnormalities were present on diffusion-weighted imaging of 17 of the 21 patients and on perfusion-weighted studies of 7 of 14 patients. The MRI results changed the preliminary/working diagnosis in six patients. In eight other patients, MRI revealed additional pathology that had not been suspected clinically, and/or characterized more closely findings that had already been detected by CT or suspected clinically. MRI showed abnormalities in four of the five patients who had normal CT. MRI findings suggested a negative clinical outcome in all nine patients who subsequently died. MRI findings also suggested positive long-term outcome in five of nine patients who improved significantly as based on Glasgow and extended Glasgow outcome scales. In the three unconscious patients who had normal diffusion- and perfusion weighted imaging the clinical outcome was good. This study suggests that MRI in seriously ill ICU patients with unclear cerebral pathology can provide information that changes, characterizes, or supports diagnoses and/or prognoses and therefore facilitates further management. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/329415
- author
- Sundgren, Pia
LU
; Reinstrup, Peter
LU
; Romner, Bertil
LU
; Holtås, Stig
LU
and Maly, Pavel
LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- perfusion-weighted studies, diffusion-weighted imaging, brain injury, magnetic resonance imaging
- in
- Neuroradiology
- volume
- 44
- issue
- 8
- pages
- 674 - 680
- publisher
- Springer
- external identifiers
-
- wos:000177751000005
- pmid:12185545
- scopus:0036939528
- ISSN
- 1432-1920
- DOI
- 10.1007/s00234-002-0777-z
- language
- English
- LU publication?
- yes
- id
- 22fd1645-dcbe-43b3-9f5b-c96b48fd8942 (old id 329415)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/12185545
- http://link.springer.com/article/10.1007%2Fs00234-002-0777-z
- date added to LUP
- 2016-04-01 11:38:00
- date last changed
- 2022-02-03 02:12:30
@article{22fd1645-dcbe-43b3-9f5b-c96b48fd8942,
abstract = {{The aim of our retrospective study was to determine the extent to which diffusion- and perfusion- weighted MRI combined with conventional MRI could be helpful in the evaluation of intensive care unit (ICU) patients who have unknown or unclear cerebral pathology underlying a serious clinical condition. Twenty-one ICU patients with disparity between the findings on brain CT scan and their clinical status were studied. All patients underwent conventional MR and diffusion-weighted imaging and 14 also had MR perfusion studies. Abnormalities were present on diffusion-weighted imaging of 17 of the 21 patients and on perfusion-weighted studies of 7 of 14 patients. The MRI results changed the preliminary/working diagnosis in six patients. In eight other patients, MRI revealed additional pathology that had not been suspected clinically, and/or characterized more closely findings that had already been detected by CT or suspected clinically. MRI showed abnormalities in four of the five patients who had normal CT. MRI findings suggested a negative clinical outcome in all nine patients who subsequently died. MRI findings also suggested positive long-term outcome in five of nine patients who improved significantly as based on Glasgow and extended Glasgow outcome scales. In the three unconscious patients who had normal diffusion- and perfusion weighted imaging the clinical outcome was good. This study suggests that MRI in seriously ill ICU patients with unclear cerebral pathology can provide information that changes, characterizes, or supports diagnoses and/or prognoses and therefore facilitates further management.}},
author = {{Sundgren, Pia and Reinstrup, Peter and Romner, Bertil and Holtås, Stig and Maly, Pavel}},
issn = {{1432-1920}},
keywords = {{perfusion-weighted studies; diffusion-weighted imaging; brain injury; magnetic resonance imaging}},
language = {{eng}},
number = {{8}},
pages = {{674--680}},
publisher = {{Springer}},
series = {{Neuroradiology}},
title = {{Value of conventional, and diffusion- and perfusion weighted MRI in the management of patients with unclear cerebral pathology, admitted to the intensive care unit}},
url = {{http://dx.doi.org/10.1007/s00234-002-0777-z}},
doi = {{10.1007/s00234-002-0777-z}},
volume = {{44}},
year = {{2002}},
}