Advanced

Carotid artery stenosis: contrast-enhanced MR angiography with two different scan times compared with digital subtraction angiography

Sundgren, PC; Sunden, P; Lindgren, Arne LU ; Lanke, Jan LU ; Holtås, Stig LU and Larsson, Elna-Marie LU (2002) In Neuroradiology 44(7). p.592-599
Abstract
Contrast enhanced magnetic resonance angiography (CE MRA) is a non-invasive alternative to conventional digital subtraction angiography (DSA). CE MRA is increasingly used as a complement to Duplex in the preoperative assessment of carotid artery stenosis. The purpose of this study was to determine if CE MRA could replace preoperative DSA. CE MRA with a scan time of 10 or 28 s was performed in 24 consecutive patients who were scheduled for preoperative DSA because of Duplex-verified severe carotid artery stenosis. Two neuroradiologists measured the degree of stenosis with three different methods, and the image quality was evaluated. DSA was used as the gold standard. For detection of severe stenosis (N. American symptomatic carotid... (More)
Contrast enhanced magnetic resonance angiography (CE MRA) is a non-invasive alternative to conventional digital subtraction angiography (DSA). CE MRA is increasingly used as a complement to Duplex in the preoperative assessment of carotid artery stenosis. The purpose of this study was to determine if CE MRA could replace preoperative DSA. CE MRA with a scan time of 10 or 28 s was performed in 24 consecutive patients who were scheduled for preoperative DSA because of Duplex-verified severe carotid artery stenosis. Two neuroradiologists measured the degree of stenosis with three different methods, and the image quality was evaluated. DSA was used as the gold standard. For detection of severe stenosis (N. American symptomatic carotid endarterectomy trial (NASCET) greater than or equal to70%; European symptomatic carotid endarterectomy trial (ECST) greater than or equal to80%; common carotid artery method (CCAM) greater than or equal to80%), the sensitivity of CE MRA maximum intensity projection (MIP) compared with DSA was 82%-100%, the specificity was 74%-93% and the accuracy was 77%-90%. The inter-observer agreement was higher, the image quality was better and the intracranial main arteries were better visualized with the 28 s than with the 10 s scan time. The enhancement of the jugular veins seen in 17% of the 10 s scans and in 58% of the patients with the 28 s scans did not interfere with the evaluation of the carotid arteries. CE MRA, preferably with a scan time of 28 s, can replace DSA in the preoperative assessment of most patients with carotid artery stenosis. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
digital subtraction angiography, magnetic resonance angiography, magnetic resonance contrast enhancement, carotid arteries, stenosis
in
Neuroradiology
volume
44
issue
7
pages
592 - 599
publisher
Springer Verlag
external identifiers
  • wos:000177370200006
  • pmid:12136361
  • scopus:0036939364
ISSN
1432-1920
DOI
10.1007/s00234-002-0789-8
language
English
LU publication?
yes
id
8c90ba0b-1566-4709-96cd-90aab95512b9 (old id 331616)
date added to LUP
2007-11-09 12:49:56
date last changed
2017-05-28 03:34:04
@article{8c90ba0b-1566-4709-96cd-90aab95512b9,
  abstract     = {Contrast enhanced magnetic resonance angiography (CE MRA) is a non-invasive alternative to conventional digital subtraction angiography (DSA). CE MRA is increasingly used as a complement to Duplex in the preoperative assessment of carotid artery stenosis. The purpose of this study was to determine if CE MRA could replace preoperative DSA. CE MRA with a scan time of 10 or 28 s was performed in 24 consecutive patients who were scheduled for preoperative DSA because of Duplex-verified severe carotid artery stenosis. Two neuroradiologists measured the degree of stenosis with three different methods, and the image quality was evaluated. DSA was used as the gold standard. For detection of severe stenosis (N. American symptomatic carotid endarterectomy trial (NASCET) greater than or equal to70%; European symptomatic carotid endarterectomy trial (ECST) greater than or equal to80%; common carotid artery method (CCAM) greater than or equal to80%), the sensitivity of CE MRA maximum intensity projection (MIP) compared with DSA was 82%-100%, the specificity was 74%-93% and the accuracy was 77%-90%. The inter-observer agreement was higher, the image quality was better and the intracranial main arteries were better visualized with the 28 s than with the 10 s scan time. The enhancement of the jugular veins seen in 17% of the 10 s scans and in 58% of the patients with the 28 s scans did not interfere with the evaluation of the carotid arteries. CE MRA, preferably with a scan time of 28 s, can replace DSA in the preoperative assessment of most patients with carotid artery stenosis.},
  author       = {Sundgren, PC and Sunden, P and Lindgren, Arne and Lanke, Jan and Holtås, Stig and Larsson, Elna-Marie},
  issn         = {1432-1920},
  keyword      = {digital subtraction angiography,magnetic resonance angiography,magnetic resonance contrast enhancement,carotid arteries,stenosis},
  language     = {eng},
  number       = {7},
  pages        = {592--599},
  publisher    = {Springer Verlag},
  series       = {Neuroradiology},
  title        = {Carotid artery stenosis: contrast-enhanced MR angiography with two different scan times compared with digital subtraction angiography},
  url          = {http://dx.doi.org/10.1007/s00234-002-0789-8},
  volume       = {44},
  year         = {2002},
}