Association between sugar intake and intima media thickness as a marker for atherosclerosis : A cross-sectional study in the Malmö diet and cancer study (Sweden)
González-Padilla, Esther LU ; Janzi, Suzanne LU ; Ramne, Stina LU
; Thuneland, Camilla
LU
; Borné, Yan
LU
and Sonestedt, Emily
LU
(2021)
In Nutrients
13(5).
- Abstract
It has been suggested that sugar intake may play a role in the development of atherosclero-sis. However, studies on this matter are lacking. Intima media thickness (IMT) is a well-established measurement of subclinical atherosclerosis. This study aimed to investigate the cross-sectional association between sugar intake (i.e., added, free and total sugar and sugar-rich foods and beverages) and IMT. Our study comprised 5269 individuals (45–73 years, 40% men) of the Malmö Diet and Cancer Study, a population-based cohort conducted in Sweden with data collected from 1991 to 1994. Measurements of IMT were performed with B-mode ultrasound at the right common carotid artery (IMTcca) and the bifurcation of the carotids (IMTbif). Dietary intake... (More)
It has been suggested that sugar intake may play a role in the development of atherosclero-sis. However, studies on this matter are lacking. Intima media thickness (IMT) is a well-established measurement of subclinical atherosclerosis. This study aimed to investigate the cross-sectional association between sugar intake (i.e., added, free and total sugar and sugar-rich foods and beverages) and IMT. Our study comprised 5269 individuals (45–73 years, 40% men) of the Malmö Diet and Cancer Study, a population-based cohort conducted in Sweden with data collected from 1991 to 1994. Measurements of IMT were performed with B-mode ultrasound at the right common carotid artery (IMTcca) and the bifurcation of the carotids (IMTbif). Dietary intake was estimated using a combina-tion of a 7-day food record, diet questionnaire and interview. After adjusting for methodological, lifestyle and dietary confounders, no statistically significant associations were observed for any of the sugar intake variables and IMT. For example, added sugar intake presented no significant linear association with IMTcca or IMTbif (Ptrends: IMTcca 0.81 for men and 0.98 for women and IMTbif 0.20 for men and 0.40 for women). In conclusion, we found no clear association between sugar intake and IMT measurements in this study.
(Less)
- author
- González-Padilla, Esther
LU
; Janzi, Suzanne
LU
; Ramne, Stina
LU
; Thuneland, Camilla
LU
; Borné, Yan
LU
and Sonestedt, Emily
LU
- organization
- publishing date
- 2021-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Added sugar, Atherosclerosis, Free sugar, IMT, Intima media thickness, SSB, Sugar intake, Sugar-rich foods, Sugar-sweetened beverages, Total sugar
- in
- Nutrients
- volume
- 13
- issue
- 5
- article number
- 1555
- publisher
- MDPI AG
- external identifiers
-
- pmid:34063058
- scopus:85105222712
- ISSN
- 2072-6643
- DOI
- 10.3390/nu13051555
- project
- The role of sugar intake in cardiovascular disease prevention
- language
- English
- LU publication?
- yes
- id
- 33f43979-c013-4a8d-bdd2-c605d276b4c3
- date added to LUP
- 2021-05-19 11:40:07
- date last changed
- 2024-04-06 03:45:12
@article{33f43979-c013-4a8d-bdd2-c605d276b4c3,
abstract = {{<p>It has been suggested that sugar intake may play a role in the development of atherosclero-sis. However, studies on this matter are lacking. Intima media thickness (IMT) is a well-established measurement of subclinical atherosclerosis. This study aimed to investigate the cross-sectional association between sugar intake (i.e., added, free and total sugar and sugar-rich foods and beverages) and IMT. Our study comprised 5269 individuals (45–73 years, 40% men) of the Malmö Diet and Cancer Study, a population-based cohort conducted in Sweden with data collected from 1991 to 1994. Measurements of IMT were performed with B-mode ultrasound at the right common carotid artery (IMTcca) and the bifurcation of the carotids (IMTbif). Dietary intake was estimated using a combina-tion of a 7-day food record, diet questionnaire and interview. After adjusting for methodological, lifestyle and dietary confounders, no statistically significant associations were observed for any of the sugar intake variables and IMT. For example, added sugar intake presented no significant linear association with IMTcca or IMTbif (P<sub>trends</sub>: IMTcca 0.81 for men and 0.98 for women and IMTbif 0.20 for men and 0.40 for women). In conclusion, we found no clear association between sugar intake and IMT measurements in this study.</p>}},
author = {{González-Padilla, Esther and Janzi, Suzanne and Ramne, Stina and Thuneland, Camilla and Borné, Yan and Sonestedt, Emily}},
issn = {{2072-6643}},
keywords = {{Added sugar; Atherosclerosis; Free sugar; IMT; Intima media thickness; SSB; Sugar intake; Sugar-rich foods; Sugar-sweetened beverages; Total sugar}},
language = {{eng}},
number = {{5}},
publisher = {{MDPI AG}},
series = {{Nutrients}},
title = {{Association between sugar intake and intima media thickness as a marker for atherosclerosis : A cross-sectional study in the Malmö diet and cancer study (Sweden)}},
url = {{http://dx.doi.org/10.3390/nu13051555}},
doi = {{10.3390/nu13051555}},
volume = {{13}},
year = {{2021}},
}