Whole-channel acoustic energy and acoustophoretic efficiency frequency spectrum by the in-flow focusing method
(2024) In Physical Review Applied 22(4).- Abstract
- The in-flow focusing method, introduced herein, enables rapid and straightforward measurements of the whole-channel acoustic energy of acoustic flow-through devices. The method is applied to assess the whole-channel acoustic energy and acoustophoretic efficiency frequency spectra of a bottom-actuated silicon-glass and a side-actuated glass chip. The input variables are the time-independent geometrical shape of the particle trajectories along the manipulation chamber, the channel cross-section geometry, the physical properties of the reference particles and fluid, and the volumetric flowrate. The outputs are the total acoustic energy, the acoustophoretic efficiency, as well as the acoustic energy density distribution along the channel,... (More)
- The in-flow focusing method, introduced herein, enables rapid and straightforward measurements of the whole-channel acoustic energy of acoustic flow-through devices. The method is applied to assess the whole-channel acoustic energy and acoustophoretic efficiency frequency spectra of a bottom-actuated silicon-glass and a side-actuated glass chip. The input variables are the time-independent geometrical shape of the particle trajectories along the manipulation chamber, the channel cross-section geometry, the physical properties of the reference particles and fluid, and the volumetric flowrate. The outputs are the total acoustic energy, the acoustophoretic efficiency, as well as the acoustic energy density distribution along the channel, which provide a comprehensive overview of the performance of acoustically driven lab-on-a-chip setups. The acoustophoretic efficiency is an important parameter that relates the energy dissipation, and therefore the heat development in the device, to the useful acoustic energy in the channel. Unlike the current state-of-the-art methods such as particle image velocimetry, particle tracking velocimetry, and optical trapping, which are typically limited to small channel areas and are time-consuming, the in-flow focusing method can be applied to long channels and enables rapid measurements of the whole-channel acoustic energy. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/34e2b6ee-8673-4778-94f7-261b38ce8830
- author
- Baasch, Thierry
LU
; Qiu, Wei
LU
and Laurell, Thomas LU
- organization
-
- Division for Biomedical Engineering
- MultiPark: Multidisciplinary research focused on Parkinson's disease
- LU Profile Area: Light and Materials
- LTH Profile Area: Nanoscience and Semiconductor Technology
- LTH Profile Area: Engineering Health
- NanoLund: Centre for Nanoscience
- LUCC: Lund University Cancer Centre
- Acoustofluidics group (research group)
- SEBRA Sepsis and Bacterial Resistance Alliance (research group)
- publishing date
- 2024-10-18
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Physical Review Applied
- volume
- 22
- issue
- 4
- article number
- 044049
- pages
- 12 pages
- publisher
- American Physical Society
- external identifiers
-
- scopus:85208479329
- ISSN
- 2331-7019
- DOI
- 10.1103/PhysRevApplied.22.044049
- language
- English
- LU publication?
- yes
- id
- 34e2b6ee-8673-4778-94f7-261b38ce8830
- date added to LUP
- 2024-11-27 22:54:17
- date last changed
- 2025-06-26 22:02:13
@article{34e2b6ee-8673-4778-94f7-261b38ce8830, abstract = {{The in-flow focusing method, introduced herein, enables rapid and straightforward measurements of the whole-channel acoustic energy of acoustic flow-through devices. The method is applied to assess the whole-channel acoustic energy and acoustophoretic efficiency frequency spectra of a bottom-actuated silicon-glass and a side-actuated glass chip. The input variables are the time-independent geometrical shape of the particle trajectories along the manipulation chamber, the channel cross-section geometry, the physical properties of the reference particles and fluid, and the volumetric flowrate. The outputs are the total acoustic energy, the acoustophoretic efficiency, as well as the acoustic energy density distribution along the channel, which provide a comprehensive overview of the performance of acoustically driven lab-on-a-chip setups. The acoustophoretic efficiency is an important parameter that relates the energy dissipation, and therefore the heat development in the device, to the useful acoustic energy in the channel. Unlike the current state-of-the-art methods such as particle image velocimetry, particle tracking velocimetry, and optical trapping, which are typically limited to small channel areas and are time-consuming, the in-flow focusing method can be applied to long channels and enables rapid measurements of the whole-channel acoustic energy.}}, author = {{Baasch, Thierry and Qiu, Wei and Laurell, Thomas}}, issn = {{2331-7019}}, language = {{eng}}, month = {{10}}, number = {{4}}, publisher = {{American Physical Society}}, series = {{Physical Review Applied}}, title = {{Whole-channel acoustic energy and acoustophoretic efficiency frequency spectrum by the in-flow focusing method}}, url = {{http://dx.doi.org/10.1103/PhysRevApplied.22.044049}}, doi = {{10.1103/PhysRevApplied.22.044049}}, volume = {{22}}, year = {{2024}}, }