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Eculizumab in an anephric patient with atypical haemolytic uraemic syndrome and advanced vascular lesions.

Békassy, Zivile LU ; Kristoffersson, Ann-Charlotte LU ; Cronqvist, Mats LU ; Roumenina, Lubka T ; Rybkine, Tania ; Vergoz, Laura ; Hue, Christophe ; Fremeaux-Bacchi, Veronique and Karpman, Diana LU orcid (2013) In Nephrology Dialysis Transplantation 28(11). p.2899-2907
Abstract
Atypical haemolytic uraemic syndrome (aHUS) is associated with dysfunction of the alternative pathway of complement. Disease activity subsides as renal failure progresses but recurs upon renal transplantation, indicating that viable renal tissue contributes to disease activity. We present evidence of cerebrovascular occlusive disease indicating that vascular injury may occur in the absence of kidneys.
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author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nephrology Dialysis Transplantation
volume
28
issue
11
pages
2899 - 2907
publisher
Oxford University Press
external identifiers
  • wos:000326747600036
  • pmid:24009284
  • scopus:84890051043
ISSN
1460-2385
DOI
10.1093/ndt/gft340
language
English
LU publication?
yes
id
35b20f68-4c9d-4d88-a4d8-5b5dd1208287 (old id 4066236)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24009284?dopt=Abstract
date added to LUP
2016-04-01 11:14:32
date last changed
2022-01-26 06:29:56
@article{35b20f68-4c9d-4d88-a4d8-5b5dd1208287,
  abstract     = {{Atypical haemolytic uraemic syndrome (aHUS) is associated with dysfunction of the alternative pathway of complement. Disease activity subsides as renal failure progresses but recurs upon renal transplantation, indicating that viable renal tissue contributes to disease activity. We present evidence of cerebrovascular occlusive disease indicating that vascular injury may occur in the absence of kidneys.}},
  author       = {{Békassy, Zivile and Kristoffersson, Ann-Charlotte and Cronqvist, Mats and Roumenina, Lubka T and Rybkine, Tania and Vergoz, Laura and Hue, Christophe and Fremeaux-Bacchi, Veronique and Karpman, Diana}},
  issn         = {{1460-2385}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{2899--2907}},
  publisher    = {{Oxford University Press}},
  series       = {{Nephrology Dialysis Transplantation}},
  title        = {{Eculizumab in an anephric patient with atypical haemolytic uraemic syndrome and advanced vascular lesions.}},
  url          = {{https://lup.lub.lu.se/search/files/2498839/4360507.pdf}},
  doi          = {{10.1093/ndt/gft340}},
  volume       = {{28}},
  year         = {{2013}},
}