Associations between Ischemic Stroke Follow-Up, Socioeconomic Status, and Adherence to Secondary Preventive Drugs in Southern Sweden : Observations from the Swedish Stroke Register (Riksstroke)
(2017) In Neuroepidemiology 48. p.32-38- Abstract
Background: Currently, the knowledge that one has on adequate stroke follow-up practices is limited. We report associations between 90-day stroke follow-up, socio-economy and adherence to secondary prevention in southern Sweden. Methods: Data on 5,602 patients with ischemic stroke January 1, 2008-December 31, 2010, were obtained from Riksstroke and linked to official registers for information on education, birth country, doctor's follow-ups, and secondary prevention. Primary adherence at 4 months and persistence at 14 months post-stroke were calculated for warfarin, statins, antihypertensive, and antiplatelet drugs. Results: The 90-day follow-up rate was 75%. Patients not receiving a 90-day follow-up had lower age-adjusted OR of... (More)
Background: Currently, the knowledge that one has on adequate stroke follow-up practices is limited. We report associations between 90-day stroke follow-up, socio-economy and adherence to secondary prevention in southern Sweden. Methods: Data on 5,602 patients with ischemic stroke January 1, 2008-December 31, 2010, were obtained from Riksstroke and linked to official registers for information on education, birth country, doctor's follow-ups, and secondary prevention. Primary adherence at 4 months and persistence at 14 months post-stroke were calculated for warfarin, statins, antihypertensive, and antiplatelet drugs. Results: The 90-day follow-up rate was 75%. Patients not receiving a 90-day follow-up had lower age-adjusted OR of persistent drug use at 14 months for antihypertensive agents (OR = 0.74, 95% CI 0.60-0.91) and for antiplatelet drugs (OR = 0.72, 95% CI 0.60-0.87). Drug adherence rates 14 months post-stroke were 85% for antiplatelet drugs, 69% for warfarin, 88% for antihypertensive agents, and 76% for statins. One in three patients discontinued using one or more drug class within 14 months, and nonadherence was associated with activities of daily living dependency at 3 months (age-adjusted OR 0.63, 95% CI 0.57-0.69), but not with age, gender, or educational status. Conclusions: The use of secondary preventive drugs decreases over the first year after stroke and remains suboptimal. Specific reasons for nonadherence warrant further study.
(Less)
- author
- Ullberg, Teresa LU ; Glader, Eva-Lotta ; Zia, Elisabet LU ; Petersson, Jesper LU ; Eriksson, M and Norrving, Bo LU
- organization
- publishing date
- 2017-02-25
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Follow-up, Ischemic stroke, Medication adherence, Secondary prevention, Socio-economic factors
- in
- Neuroepidemiology
- volume
- 48
- pages
- 7 pages
- publisher
- Karger
- external identifiers
-
- scopus:85014075996
- pmid:28237982
- wos:000403361900004
- ISSN
- 0251-5350
- DOI
- 10.1159/000456618
- language
- English
- LU publication?
- yes
- id
- 367bdc6f-02fb-4343-8c04-c7b747744144
- date added to LUP
- 2017-03-13 10:57:57
- date last changed
- 2025-02-17 12:54:45
@article{367bdc6f-02fb-4343-8c04-c7b747744144,
abstract = {{<p>Background: Currently, the knowledge that one has on adequate stroke follow-up practices is limited. We report associations between 90-day stroke follow-up, socio-economy and adherence to secondary prevention in southern Sweden. Methods: Data on 5,602 patients with ischemic stroke January 1, 2008-December 31, 2010, were obtained from Riksstroke and linked to official registers for information on education, birth country, doctor's follow-ups, and secondary prevention. Primary adherence at 4 months and persistence at 14 months post-stroke were calculated for warfarin, statins, antihypertensive, and antiplatelet drugs. Results: The 90-day follow-up rate was 75%. Patients not receiving a 90-day follow-up had lower age-adjusted OR of persistent drug use at 14 months for antihypertensive agents (OR = 0.74, 95% CI 0.60-0.91) and for antiplatelet drugs (OR = 0.72, 95% CI 0.60-0.87). Drug adherence rates 14 months post-stroke were 85% for antiplatelet drugs, 69% for warfarin, 88% for antihypertensive agents, and 76% for statins. One in three patients discontinued using one or more drug class within 14 months, and nonadherence was associated with activities of daily living dependency at 3 months (age-adjusted OR 0.63, 95% CI 0.57-0.69), but not with age, gender, or educational status. Conclusions: The use of secondary preventive drugs decreases over the first year after stroke and remains suboptimal. Specific reasons for nonadherence warrant further study.</p>}},
author = {{Ullberg, Teresa and Glader, Eva-Lotta and Zia, Elisabet and Petersson, Jesper and Eriksson, M and Norrving, Bo}},
issn = {{0251-5350}},
keywords = {{Follow-up; Ischemic stroke; Medication adherence; Secondary prevention; Socio-economic factors}},
language = {{eng}},
month = {{02}},
pages = {{32--38}},
publisher = {{Karger}},
series = {{Neuroepidemiology}},
title = {{Associations between Ischemic Stroke Follow-Up, Socioeconomic Status, and Adherence to Secondary Preventive Drugs in Southern Sweden : Observations from the Swedish Stroke Register (Riksstroke)}},
url = {{http://dx.doi.org/10.1159/000456618}},
doi = {{10.1159/000456618}},
volume = {{48}},
year = {{2017}},
}