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Inflammatory markers and mortality in critical lower limb ischemia

Gottsäter, Anders LU (2013) p.91-96
Abstract

In atherosclerotic vascular disease, endothelial dysfunction is induced by risk factors such as arterial hypertension, hypercholesterolemia, and tobacco use. In fl ammatory mechanisms and in fl ammatory cytokines play important roles in all of these mechanisms, and the different steps in atherogenesis involve cytokines as in fl ammatory promoters, stimulating the expression of proatherogenic genes in endothelial cells [1, 2]. Important cytokines are, for example, tumor necrosis factor a [3], neopterin [4], and interleukin-6 [3, 5]. Expression of the immune mediator CD40 ligand is increased in atherogenesis [6, 7], and prostaglandin-like isoprostanes [8, 9] are markers of lipid peroxidation and believed to contribute to atherosclerosis... (More)

In atherosclerotic vascular disease, endothelial dysfunction is induced by risk factors such as arterial hypertension, hypercholesterolemia, and tobacco use. In fl ammatory mechanisms and in fl ammatory cytokines play important roles in all of these mechanisms, and the different steps in atherogenesis involve cytokines as in fl ammatory promoters, stimulating the expression of proatherogenic genes in endothelial cells [1, 2]. Important cytokines are, for example, tumor necrosis factor a [3], neopterin [4], and interleukin-6 [3, 5]. Expression of the immune mediator CD40 ligand is increased in atherogenesis [6, 7], and prostaglandin-like isoprostanes [8, 9] are markers of lipid peroxidation and believed to contribute to atherosclerosis and thrombosis [10].

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Inflammatory Response in Cardiovascular Surgery
editor
Gabriel, Edmo A. and Gabriel, Sthefano A.
pages
6 pages
publisher
Springer
external identifiers
  • scopus:84956521154
ISBN
9781447144281
9781447144298
language
English
LU publication?
yes
id
377dd36f-de06-45f0-add8-0001821eebc8
alternative location
https://link.springer.com/chapter/10.1007/978-1-4471-4429-8_13
date added to LUP
2020-12-11 14:08:58
date last changed
2024-01-03 00:43:29
@inbook{377dd36f-de06-45f0-add8-0001821eebc8,
  abstract     = {{<p>In atherosclerotic vascular disease, endothelial dysfunction is induced by risk factors such as arterial hypertension, hypercholesterolemia, and tobacco use. In fl ammatory mechanisms and in fl ammatory cytokines play important roles in all of these mechanisms, and the different steps in atherogenesis involve cytokines as in fl ammatory promoters, stimulating the expression of proatherogenic genes in endothelial cells [1, 2]. Important cytokines are, for example, tumor necrosis factor a [3], neopterin [4], and interleukin-6 [3, 5]. Expression of the immune mediator CD40 ligand is increased in atherogenesis [6, 7], and prostaglandin-like isoprostanes [8, 9] are markers of lipid peroxidation and believed to contribute to atherosclerosis and thrombosis [10].</p>}},
  author       = {{Gottsäter, Anders}},
  booktitle    = {{Inflammatory Response in Cardiovascular Surgery}},
  editor       = {{Gabriel, Edmo A. and Gabriel, Sthefano A.}},
  isbn         = {{9781447144281}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{91--96}},
  publisher    = {{Springer}},
  title        = {{Inflammatory markers and mortality in critical lower limb ischemia}},
  url          = {{https://link.springer.com/chapter/10.1007/978-1-4471-4429-8_13}},
  year         = {{2013}},
}