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Bulk laxatives : their dietary fibre composition, degradation, and faecal bulking capacity in the rat

Nyman, M LU and Asp, N G LU (1985) In Scandinavian Journal of Gastroenterology 20(7). p.95-887
Abstract

The intestinal dietary fibre degradation and faecal bulking capacity of various bulk laxatives were investigated by means of balance experiments on rats. Nitrogen, fat, and mineral excretion in faeces was also studied. The dietary fibre content of the various bulk laxatives was quite different (in g/kg dry matter): ACO fibre tablets (barley and citrus pulp), 451; Fiberform (wheat bran-based), 817; Inolaxol (sterkulia gum), 696; and Vi-Siblin (ispaghula husk), 533. The increase in faecal dry matter per 1 g dietary fibre was similar with ACO fibre tablets, Fiberform, and Vi-Siblin. Inolaxol gave a significantly (p less than 0.001) higher faecal dry-weight increment, mainly due to an increased mineral excretion. Of the dry-weight... (More)

The intestinal dietary fibre degradation and faecal bulking capacity of various bulk laxatives were investigated by means of balance experiments on rats. Nitrogen, fat, and mineral excretion in faeces was also studied. The dietary fibre content of the various bulk laxatives was quite different (in g/kg dry matter): ACO fibre tablets (barley and citrus pulp), 451; Fiberform (wheat bran-based), 817; Inolaxol (sterkulia gum), 696; and Vi-Siblin (ispaghula husk), 533. The increase in faecal dry matter per 1 g dietary fibre was similar with ACO fibre tablets, Fiberform, and Vi-Siblin. Inolaxol gave a significantly (p less than 0.001) higher faecal dry-weight increment, mainly due to an increased mineral excretion. Of the dry-weight increment, 59-82% constituted undegraded dietary fibre. Thus, 68-97% of the fibre passed through the gastrointestinal tract without being degraded. All the bulk laxatives caused a similar increase in the faecal N content, whereas the increase in faecal lipids was most pronounced with Vi-Siblin. The water-holding capacity of faeces was more pronounced with Inolaxol and Vi-Siblin than with ACO fibre tablets and Fiberform.

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author
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organization
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type
Contribution to journal
publication status
published
subject
keywords
Animals, Cathartics/analysis, Dietary Fiber/analysis, Intestines/metabolism, Lipid Metabolism, Minerals/metabolism, Molecular Conformation, Molecular Weight, Nitrogen/metabolism, Rats, Solubility, Technology, Pharmaceutical
in
Scandinavian Journal of Gastroenterology
volume
20
issue
7
pages
9 pages
publisher
Taylor & Francis
external identifiers
  • scopus:0021883127
  • pmid:2996120
ISSN
0036-5521
DOI
10.3109/00365528509088841
language
English
LU publication?
yes
id
3879c1dd-abf0-4666-9d73-e78c1248e8c2
date added to LUP
2018-10-16 18:34:21
date last changed
2024-01-15 04:13:53
@article{3879c1dd-abf0-4666-9d73-e78c1248e8c2,
  abstract     = {{<p>The intestinal dietary fibre degradation and faecal bulking capacity of various bulk laxatives were investigated by means of balance experiments on rats. Nitrogen, fat, and mineral excretion in faeces was also studied. The dietary fibre content of the various bulk laxatives was quite different (in g/kg dry matter): ACO fibre tablets (barley and citrus pulp), 451; Fiberform (wheat bran-based), 817; Inolaxol (sterkulia gum), 696; and Vi-Siblin (ispaghula husk), 533. The increase in faecal dry matter per 1 g dietary fibre was similar with ACO fibre tablets, Fiberform, and Vi-Siblin. Inolaxol gave a significantly (p less than 0.001) higher faecal dry-weight increment, mainly due to an increased mineral excretion. Of the dry-weight increment, 59-82% constituted undegraded dietary fibre. Thus, 68-97% of the fibre passed through the gastrointestinal tract without being degraded. All the bulk laxatives caused a similar increase in the faecal N content, whereas the increase in faecal lipids was most pronounced with Vi-Siblin. The water-holding capacity of faeces was more pronounced with Inolaxol and Vi-Siblin than with ACO fibre tablets and Fiberform.</p>}},
  author       = {{Nyman, M and Asp, N G}},
  issn         = {{0036-5521}},
  keywords     = {{Animals; Cathartics/analysis; Dietary Fiber/analysis; Intestines/metabolism; Lipid Metabolism; Minerals/metabolism; Molecular Conformation; Molecular Weight; Nitrogen/metabolism; Rats; Solubility; Technology, Pharmaceutical}},
  language     = {{eng}},
  number       = {{7}},
  pages        = {{95--887}},
  publisher    = {{Taylor & Francis}},
  series       = {{Scandinavian Journal of Gastroenterology}},
  title        = {{Bulk laxatives : their dietary fibre composition, degradation, and faecal bulking capacity in the rat}},
  url          = {{http://dx.doi.org/10.3109/00365528509088841}},
  doi          = {{10.3109/00365528509088841}},
  volume       = {{20}},
  year         = {{1985}},
}