Advanced

Seasonal Pattern in the Diagnosis of Gestational Diabetes Mellitus in Southern Sweden

Katsarou, Anastasia LU ; Claesson, Rickard LU ; Ignell, Claes LU ; Shaat, Nael LU and Berntorp, Kerstin LU (2016) In Journal of Diabetes Research 2016.
Abstract

Aim. The aim of this study was to examine seasonal patterns in glucose tolerance and in the diagnosis of gestational diabetes mellitus (GDM). Methods. Altogether, 11 538 women underwent a 75-g oral glucose tolerance test (OGTT) in the twenty-eighth week of pregnancy during the years 2003-2005 in southern Sweden. GDM was defined by the 2-h capillary glucose concentration in the OGTT (≥8.9 mmol/L). Chi-squared test, analysis of variance, and regression analyses were used for statistical evaluations. Results. The seasonal frequency of GDM ranged from 3.3% in spring to 5.5% in summer (p<0.0001). Mean 2-h glucose concentrations followed the same seasonal trend, with a difference of 0.15 mmol/L between winter and summer (p<0.0001). The... (More)

Aim. The aim of this study was to examine seasonal patterns in glucose tolerance and in the diagnosis of gestational diabetes mellitus (GDM). Methods. Altogether, 11 538 women underwent a 75-g oral glucose tolerance test (OGTT) in the twenty-eighth week of pregnancy during the years 2003-2005 in southern Sweden. GDM was defined by the 2-h capillary glucose concentration in the OGTT (≥8.9 mmol/L). Chi-squared test, analysis of variance, and regression analyses were used for statistical evaluations. Results. The seasonal frequency of GDM ranged from 3.3% in spring to 5.5% in summer (p<0.0001). Mean 2-h glucose concentrations followed the same seasonal trend, with a difference of 0.15 mmol/L between winter and summer (p<0.0001). The 2-h glucose level increased by 0.009 mmol/L for every degree increase in temperature (p<0.0001). In regression analysis, summer (June-August) was associated with increased 2-h glucose level (p<0.001) and increased frequency of GDM compared to the other seasons (odds ratio 1.51, 95% confidence interval 1.24-1.83, and p<0.001). Conclusions. Our findings suggest seasonal variation in the 2-h glucose concentration in the OGTT and in the proportion of women diagnosed with GDM, with a peak in the summer.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Diabetes Research
volume
2016
publisher
Hindawi Publishing Corporation
external identifiers
  • scopus:85009359405
  • wos:000391994000001
ISSN
2314-6745
DOI
10.1155/2016/8905474
language
English
LU publication?
yes
id
3a42b9df-de94-43c5-a307-8b4864199a9d
date added to LUP
2017-02-10 14:08:29
date last changed
2017-09-18 11:37:52
@article{3a42b9df-de94-43c5-a307-8b4864199a9d,
  abstract     = {<p>Aim. The aim of this study was to examine seasonal patterns in glucose tolerance and in the diagnosis of gestational diabetes mellitus (GDM). Methods. Altogether, 11 538 women underwent a 75-g oral glucose tolerance test (OGTT) in the twenty-eighth week of pregnancy during the years 2003-2005 in southern Sweden. GDM was defined by the 2-h capillary glucose concentration in the OGTT (≥8.9 mmol/L). Chi-squared test, analysis of variance, and regression analyses were used for statistical evaluations. Results. The seasonal frequency of GDM ranged from 3.3% in spring to 5.5% in summer (p&lt;0.0001). Mean 2-h glucose concentrations followed the same seasonal trend, with a difference of 0.15 mmol/L between winter and summer (p&lt;0.0001). The 2-h glucose level increased by 0.009 mmol/L for every degree increase in temperature (p&lt;0.0001). In regression analysis, summer (June-August) was associated with increased 2-h glucose level (p&lt;0.001) and increased frequency of GDM compared to the other seasons (odds ratio 1.51, 95% confidence interval 1.24-1.83, and p&lt;0.001). Conclusions. Our findings suggest seasonal variation in the 2-h glucose concentration in the OGTT and in the proportion of women diagnosed with GDM, with a peak in the summer.</p>},
  articleno    = {8905474},
  author       = {Katsarou, Anastasia and Claesson, Rickard and Ignell, Claes and Shaat, Nael and Berntorp, Kerstin},
  issn         = {2314-6745},
  language     = {eng},
  publisher    = {Hindawi Publishing Corporation},
  series       = {Journal of Diabetes Research},
  title        = {Seasonal Pattern in the Diagnosis of Gestational Diabetes Mellitus in Southern Sweden},
  url          = {http://dx.doi.org/10.1155/2016/8905474},
  volume       = {2016},
  year         = {2016},
}