Hypophyseal tumor and gynecomastia preceding bilateral breast cancer development in a man
Olsson, Hakan LU
; Alm, Per
LU
; Kristoffersson, Ulf
LU
and Landin‐Olsson, Mona
LU
(1984)
In Cancer
53(9).
p.1974-1977
- Abstract
The case is reported of a 48‐year‐old man who, 26 years after treatment for a hypophyseal tumor and 11 years after the onset of bilateral gynecomastia, developed cancer of the left breast. Ten years after the first breast cancer operation a new cancer developed in his right breast. Hormonal investigation at the time of the second breast cancer operation revealed a low S‐FSH and a relative estrogen excess compared to testosterone. Values of thyroid and adrenal hormones were essentially normal, while P‐prolactin was elevated. Stimulatory tests of the hypophyseal function were in accordance with a partial hypophyseal insufficiency affecting the hypophyseal‐gonadal axis. Also, a weak elevation of S‐HGH was noted by an insulin tolerance... (More)
The case is reported of a 48‐year‐old man who, 26 years after treatment for a hypophyseal tumor and 11 years after the onset of bilateral gynecomastia, developed cancer of the left breast. Ten years after the first breast cancer operation a new cancer developed in his right breast. Hormonal investigation at the time of the second breast cancer operation revealed a low S‐FSH and a relative estrogen excess compared to testosterone. Values of thyroid and adrenal hormones were essentially normal, while P‐prolactin was elevated. Stimulatory tests of the hypophyseal function were in accordance with a partial hypophyseal insufficiency affecting the hypophyseal‐gonadal axis. Also, a weak elevation of S‐HGH was noted by an insulin tolerance test. Immunohistochemical analysis of the pituitary tumor 36 years later showed that the tumor could be classified as a prolactinoma. Cytogenetic analysis revealed a normal male chromosome karyotype.
(Less)
- author
- Olsson, Hakan
LU
; Alm, Per
LU
; Kristoffersson, Ulf
LU
and Landin‐Olsson, Mona
LU
- organization
- publishing date
- 1984-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cancer
- volume
- 53
- issue
- 9
- pages
- 1974 - 1977
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:0021164773
- pmid:6704924
- ISSN
- 0008-543X
- DOI
- 10.1002/1097-0142(19840501)53:9<1974::AID-CNCR2820530928>3.0.CO;2-G
- language
- English
- LU publication?
- yes
- id
- 3b0c9265-d403-4742-a36c-0c6d3aa2f532
- date added to LUP
- 2018-12-17 10:45:37
- date last changed
- 2025-10-14 09:10:17
@article{3b0c9265-d403-4742-a36c-0c6d3aa2f532,
abstract = {{<p>The case is reported of a 48‐year‐old man who, 26 years after treatment for a hypophyseal tumor and 11 years after the onset of bilateral gynecomastia, developed cancer of the left breast. Ten years after the first breast cancer operation a new cancer developed in his right breast. Hormonal investigation at the time of the second breast cancer operation revealed a low S‐FSH and a relative estrogen excess compared to testosterone. Values of thyroid and adrenal hormones were essentially normal, while P‐prolactin was elevated. Stimulatory tests of the hypophyseal function were in accordance with a partial hypophyseal insufficiency affecting the hypophyseal‐gonadal axis. Also, a weak elevation of S‐HGH was noted by an insulin tolerance test. Immunohistochemical analysis of the pituitary tumor 36 years later showed that the tumor could be classified as a prolactinoma. Cytogenetic analysis revealed a normal male chromosome karyotype.</p>}},
author = {{Olsson, Hakan and Alm, Per and Kristoffersson, Ulf and Landin‐Olsson, Mona}},
issn = {{0008-543X}},
language = {{eng}},
month = {{01}},
number = {{9}},
pages = {{1974--1977}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Cancer}},
title = {{Hypophyseal tumor and gynecomastia preceding bilateral breast cancer development in a man}},
url = {{http://dx.doi.org/10.1002/1097-0142(19840501)53:9<1974::AID-CNCR2820530928>3.0.CO;2-G}},
doi = {{10.1002/1097-0142(19840501)53:9<1974::AID-CNCR2820530928>3.0.CO;2-G}},
volume = {{53}},
year = {{1984}},
}