Ciprofloxacin does not inhibit mitochondrial functions but other antiboitics do
Riesbeck, K. LU
; Bredberg, A.
LU
and Forsgren, A.
LU
(1990)
In Antimicrobial Agents and Chemotherapy
34(1).
p.167-169
- Abstract
At clinical concentrations, ciprofloxacin did not inhibit mitochondrial DNA replication, oxidative phosphorylation, protein synthesis, or mitochondrial mass (transmembrane potential). No difference in supercoiled forms of DNA was observed. The tetracyclines and chloramphenicol inhibited protein synthesis at clinically achievable concentrations, while rifampin, fusidic acid, and clindamycin did not.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3d189daa-ce3d-4f7e-8083-62ab1c788c3a
- author
- Riesbeck, K.
LU
; Bredberg, A.
LU
and Forsgren, A.
LU
- organization
- publishing date
- 1990-01-01
- type
- Contribution to journal
- publication status
- published
- in
- Antimicrobial Agents and Chemotherapy
- volume
- 34
- issue
- 1
- pages
- 167 - 169
- publisher
- American Society for Microbiology
- external identifiers
-
- pmid:2327755
- scopus:0025099701
- ISSN
- 0066-4804
- DOI
- 10.1128/AAC.34.1.167
- language
- English
- LU publication?
- yes
- id
- 3d189daa-ce3d-4f7e-8083-62ab1c788c3a
- date added to LUP
- 2019-03-22 11:01:24
- date last changed
- 2024-01-01 00:12:17
@article{3d189daa-ce3d-4f7e-8083-62ab1c788c3a,
abstract = {{<p>At clinical concentrations, ciprofloxacin did not inhibit mitochondrial DNA replication, oxidative phosphorylation, protein synthesis, or mitochondrial mass (transmembrane potential). No difference in supercoiled forms of DNA was observed. The tetracyclines and chloramphenicol inhibited protein synthesis at clinically achievable concentrations, while rifampin, fusidic acid, and clindamycin did not.</p>}},
author = {{Riesbeck, K. and Bredberg, A. and Forsgren, A.}},
issn = {{0066-4804}},
language = {{eng}},
month = {{01}},
number = {{1}},
pages = {{167--169}},
publisher = {{American Society for Microbiology}},
series = {{Antimicrobial Agents and Chemotherapy}},
title = {{Ciprofloxacin does not inhibit mitochondrial functions but other antiboitics do}},
url = {{http://dx.doi.org/10.1128/AAC.34.1.167}},
doi = {{10.1128/AAC.34.1.167}},
volume = {{34}},
year = {{1990}},
}