The clinical significance of 10-m walk test standardizations in Parkinson’s disease
Lindholm, Beata LU ; Nilsson, Maria H. LU
; Hansson, Oskar
LU
and Hagell, Peter
LU
(2018)
In Journal of Neurology
265(8).
p.1829-1835
- Abstract
Background: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson’s disease (PD). However, it is unclear if different standardizations of its conduct impact test results. Aim of the study: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall prediction were also explored. Methods: 151 people with PD (mean age and PD duration, 68 and 4 years, respectively) completed the 10MWT in comfortable gait speed with static and dynamic start (two trials each), and gait speed (m/s) was recorded. Participants then registered all prospective falls for 6 months. Results: Absolute mean differences... (More)
Background: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson’s disease (PD). However, it is unclear if different standardizations of its conduct impact test results. Aim of the study: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall prediction were also explored. Methods: 151 people with PD (mean age and PD duration, 68 and 4 years, respectively) completed the 10MWT in comfortable gait speed with static and dynamic start (two trials each), and gait speed (m/s) was recorded. Participants then registered all prospective falls for 6 months. Results: Absolute mean differences between outcomes from the various test conditions ranged between 0.016 and 0.040 m/s (effect sizes, 0.06–0.14) with high levels of agreement (intra-class correlation coefficients, 0.932–0.987) and small standard errors of measurement (0.032–0.076 m/s). Receiver operating characteristic curves showed similar discriminate abilities for prediction of future falls across conditions (areas under curves, 0.70–0.73). Cut-off points were estimated at 1.1–1.2 m/s. Conclusions: Different 10MWT standardizations yield very similar results, suggesting that there is no practical need for an acceleration distance or repeated trials when conducting this test in mild PD.
(Less)
- author
- Lindholm, Beata
LU
; Nilsson, Maria H.
LU
; Hansson, Oskar
LU
and Hagell, Peter
LU
- organization
- publishing date
- 2018-06-06
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Falls, Parkinson disease, Prediction, Test standardization, The 10-m walk test
- in
- Journal of Neurology
- volume
- 265
- issue
- 8
- pages
- 1829 - 1835
- publisher
- Springer
- external identifiers
-
- scopus:85048050349
- pmid:29876762
- ISSN
- 0340-5354
- DOI
- 10.1007/s00415-018-8921-9
- language
- English
- LU publication?
- yes
- id
- 3dbb077f-78cd-4bee-bb29-70a0cde9336b
- date added to LUP
- 2018-06-18 16:13:10
- date last changed
- 2024-06-25 18:40:23
@article{3dbb077f-78cd-4bee-bb29-70a0cde9336b,
abstract = {{<p>Background: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson’s disease (PD). However, it is unclear if different standardizations of its conduct impact test results. Aim of the study: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall prediction were also explored. Methods: 151 people with PD (mean age and PD duration, 68 and 4 years, respectively) completed the 10MWT in comfortable gait speed with static and dynamic start (two trials each), and gait speed (m/s) was recorded. Participants then registered all prospective falls for 6 months. Results: Absolute mean differences between outcomes from the various test conditions ranged between 0.016 and 0.040 m/s (effect sizes, 0.06–0.14) with high levels of agreement (intra-class correlation coefficients, 0.932–0.987) and small standard errors of measurement (0.032–0.076 m/s). Receiver operating characteristic curves showed similar discriminate abilities for prediction of future falls across conditions (areas under curves, 0.70–0.73). Cut-off points were estimated at 1.1–1.2 m/s. Conclusions: Different 10MWT standardizations yield very similar results, suggesting that there is no practical need for an acceleration distance or repeated trials when conducting this test in mild PD.</p>}},
author = {{Lindholm, Beata and Nilsson, Maria H. and Hansson, Oskar and Hagell, Peter}},
issn = {{0340-5354}},
keywords = {{Falls; Parkinson disease; Prediction; Test standardization; The 10-m walk test}},
language = {{eng}},
month = {{06}},
number = {{8}},
pages = {{1829--1835}},
publisher = {{Springer}},
series = {{Journal of Neurology}},
title = {{The clinical significance of 10-m walk test standardizations in Parkinson’s disease}},
url = {{http://dx.doi.org/10.1007/s00415-018-8921-9}},
doi = {{10.1007/s00415-018-8921-9}},
volume = {{265}},
year = {{2018}},
}