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Regulation of stroke-induced neurogenesis in adult brain--recent scientific progress.

Kokaia, Zaal LU ; Thored, Pär LU ; Arvidsson, Andreas LU and Lindvall, Olle LU (2006) Progress in Corticogenesis In Cerebral Cortex 16. p.162-167
Abstract
Stroke induced by middle cerebral artery occlusion in adult rodents induces the formation of new neurons in the damaged striatum, a region that normally does not show neurogenesis. Here we describe recent findings on the regulation of neurogenesis after stroke, in particular regarding the duration of the neurogenic response and the influence of age, as well as the molecular mechanisms influencing migration and survival of the new neurons. We also discuss some crucial issues that need to be addressed in the further exploration of this potential self-repair mechanism after damage to the adult brain.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
striatum, stroke, neurogenesis, neural stem cells, migration, subventricular zone
in
Cerebral Cortex
volume
16
pages
162 - 167
publisher
Oxford University Press
conference name
Progress in Corticogenesis
external identifiers
  • wos:000238959500020
  • wos:000238563900020
  • scopus:33746783060
ISSN
1460-2199
DOI
10.1093/cercor/bhj174
language
English
LU publication?
yes
id
1252fbec-4889-40f7-a245-3d1176948a3f (old id 402287)
date added to LUP
2007-07-16 10:59:01
date last changed
2017-08-06 05:08:20
@article{1252fbec-4889-40f7-a245-3d1176948a3f,
  abstract     = {Stroke induced by middle cerebral artery occlusion in adult rodents induces the formation of new neurons in the damaged striatum, a region that normally does not show neurogenesis. Here we describe recent findings on the regulation of neurogenesis after stroke, in particular regarding the duration of the neurogenic response and the influence of age, as well as the molecular mechanisms influencing migration and survival of the new neurons. We also discuss some crucial issues that need to be addressed in the further exploration of this potential self-repair mechanism after damage to the adult brain.},
  author       = {Kokaia, Zaal and Thored, Pär and Arvidsson, Andreas and Lindvall, Olle},
  issn         = {1460-2199},
  keyword      = {striatum,stroke,neurogenesis,neural stem cells,migration,subventricular zone},
  language     = {eng},
  pages        = {162--167},
  publisher    = {Oxford University Press},
  series       = {Cerebral Cortex},
  title        = {Regulation of stroke-induced neurogenesis in adult brain--recent scientific progress.},
  url          = {http://dx.doi.org/10.1093/cercor/bhj174},
  volume       = {16},
  year         = {2006},
}