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Differential impedance spectra analysis reveals optimal actuation frequency in bulk mode acoustophoresis

Vitali, Valentina LU ; Core, Giulia ; Garofalo, Fabio LU ; Laurell, Thomas LU and Lenshof, Andreas LU (2019) In Scientific Reports 9(1).
Abstract

This work reports a method to select the optimal working frequency in transversal bulk resonator acoustophoretic devices by electrical impedance measurements. The impedance spectra of acoustophoretic devices are rich in spurious resonance peaks originating from different resonance modes in the system not directly related to the channel resonance, why direct measurement of the piezoelectric transducer impedance spectra is not a viable strategy. This work presents, for the first time, that the resonance modes of microchip integrated acoustophoresis channels can be identified by sequentially measuring the impedance spectra of the acoustophoretic device when the channel is filled with two different fluids and subsequently calculate the... (More)

This work reports a method to select the optimal working frequency in transversal bulk resonator acoustophoretic devices by electrical impedance measurements. The impedance spectra of acoustophoretic devices are rich in spurious resonance peaks originating from different resonance modes in the system not directly related to the channel resonance, why direct measurement of the piezoelectric transducer impedance spectra is not a viable strategy. This work presents, for the first time, that the resonance modes of microchip integrated acoustophoresis channels can be identified by sequentially measuring the impedance spectra of the acoustophoretic device when the channel is filled with two different fluids and subsequently calculate the Normalized Differential Spectrum (NDS). Seven transversal bulk resonator acoustophoretic devices of different materials and designs were tested with successful results. The developed method enables a rapid, reproducible and precise determination of the optimal working frequency.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scientific Reports
volume
9
issue
1
article number
19081
publisher
Nature Publishing Group
external identifiers
  • scopus:85076522738
  • pmid:31836756
ISSN
2045-2322
DOI
10.1038/s41598-019-55333-1
language
English
LU publication?
yes
id
402c06c3-72fe-4acb-a4a4-a5ce480ad02b
date added to LUP
2020-01-07 14:08:28
date last changed
2024-05-01 03:21:49
@article{402c06c3-72fe-4acb-a4a4-a5ce480ad02b,
  abstract     = {{<p>This work reports a method to select the optimal working frequency in transversal bulk resonator acoustophoretic devices by electrical impedance measurements. The impedance spectra of acoustophoretic devices are rich in spurious resonance peaks originating from different resonance modes in the system not directly related to the channel resonance, why direct measurement of the piezoelectric transducer impedance spectra is not a viable strategy. This work presents, for the first time, that the resonance modes of microchip integrated acoustophoresis channels can be identified by sequentially measuring the impedance spectra of the acoustophoretic device when the channel is filled with two different fluids and subsequently calculate the Normalized Differential Spectrum (NDS). Seven transversal bulk resonator acoustophoretic devices of different materials and designs were tested with successful results. The developed method enables a rapid, reproducible and precise determination of the optimal working frequency.</p>}},
  author       = {{Vitali, Valentina and Core, Giulia and Garofalo, Fabio and Laurell, Thomas and Lenshof, Andreas}},
  issn         = {{2045-2322}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Scientific Reports}},
  title        = {{Differential impedance spectra analysis reveals optimal actuation frequency in bulk mode acoustophoresis}},
  url          = {{http://dx.doi.org/10.1038/s41598-019-55333-1}},
  doi          = {{10.1038/s41598-019-55333-1}},
  volume       = {{9}},
  year         = {{2019}},
}