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Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.

Larsson, Helena LU ; Vehik, Kendra LU ; Gesualdo, Patricia; Akolkar, Beena; Hagopian, William; Krischer, Jeffery; Lernmark, Åke LU ; Rewers, Marian; Simell, Olli and She, Jin-Xiong, et al. (2014) In Pediatric Diabetes 15(2). p.118-126
Abstract
The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed at an early stage of disease, (ii) a high proportion are diagnosed by an oral glucose tolerance test (OGTT), and (iii) risk for early T1D is related to country, population, human leukocyte antigen (HLA)-genotypes and immunological markers.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pediatric Diabetes
volume
15
issue
2
pages
118 - 126
publisher
Wiley-Blackwell
external identifiers
  • pmid:24034790
  • wos:000333060300006
  • scopus:84896395566
ISSN
1399-543X
DOI
10.1111/pedi.12066
language
English
LU publication?
yes
id
53b79938-4529-427b-a206-10a92e715abd (old id 4065855)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24034790?dopt=Abstract
date added to LUP
2013-10-02 18:56:48
date last changed
2017-11-12 03:14:23
@article{53b79938-4529-427b-a206-10a92e715abd,
  abstract     = {The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed at an early stage of disease, (ii) a high proportion are diagnosed by an oral glucose tolerance test (OGTT), and (iii) risk for early T1D is related to country, population, human leukocyte antigen (HLA)-genotypes and immunological markers.},
  author       = {Larsson, Helena and Vehik, Kendra and Gesualdo, Patricia and Akolkar, Beena and Hagopian, William and Krischer, Jeffery and Lernmark, Åke and Rewers, Marian and Simell, Olli and She, Jin-Xiong and Ziegler, Anette and Haller, Michael J},
  issn         = {1399-543X},
  language     = {eng},
  number       = {2},
  pages        = {118--126},
  publisher    = {Wiley-Blackwell},
  series       = {Pediatric Diabetes},
  title        = {Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.},
  url          = {http://dx.doi.org/10.1111/pedi.12066},
  volume       = {15},
  year         = {2014},
}