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Intensified Tuberculosis Case-Finding in HIV-Positive Adults Managed at Ethiopian Health Centers: Diagnostic Yield of Xpert MTB/RIF Compared with Smear Microscopy and Liquid Culture.

Balcha, Taye LU ; Sturegård, Erik LU ; Winqvist, Niclas LU ; Skogmar, Sten LU ; Reepalu, Anton LU ; Jemal, Zelalem Habtamu; Tibesso, Gudeta; Schön, Thomas and Björkman, Per LU (2014) In PLoS ONE 9(1).
Abstract
Detection of active tuberculosis (TB) before antiretroviral therapy (ART) initiation is important, but optimal diagnostic methods for use in resource-limited settings are lacking. We assessed the prevalence of TB, evaluated the diagnostic yield of Xpert MTB/RIF in comparison with smear microscopy and culture, and the impact of Xpert results on clinical management in HIV-positive adults eligible for ART at health centers in a region of Ethiopia.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
9
issue
1
publisher
Public Library of Science
external identifiers
  • pmid:24465572
  • wos:000330283100042
  • scopus:84899839132
ISSN
1932-6203
DOI
10.1371/journal.pone.0085478
language
English
LU publication?
yes
id
8aea1b54-5502-4222-a9eb-0ed718a18690 (old id 4290621)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24465572?dopt=Abstract
date added to LUP
2014-02-07 18:40:00
date last changed
2017-10-29 03:52:22
@article{8aea1b54-5502-4222-a9eb-0ed718a18690,
  abstract     = {Detection of active tuberculosis (TB) before antiretroviral therapy (ART) initiation is important, but optimal diagnostic methods for use in resource-limited settings are lacking. We assessed the prevalence of TB, evaluated the diagnostic yield of Xpert MTB/RIF in comparison with smear microscopy and culture, and the impact of Xpert results on clinical management in HIV-positive adults eligible for ART at health centers in a region of Ethiopia.},
  articleno    = {e85478},
  author       = {Balcha, Taye and Sturegård, Erik and Winqvist, Niclas and Skogmar, Sten and Reepalu, Anton and Jemal, Zelalem Habtamu and Tibesso, Gudeta and Schön, Thomas and Björkman, Per},
  issn         = {1932-6203},
  language     = {eng},
  number       = {1},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Intensified Tuberculosis Case-Finding in HIV-Positive Adults Managed at Ethiopian Health Centers: Diagnostic Yield of Xpert MTB/RIF Compared with Smear Microscopy and Liquid Culture.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0085478},
  volume       = {9},
  year         = {2014},
}