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A novel framework for classification of selection processes in epidemiological research

Björk, Jonas LU ; Nilsson, Anton LU ; Bonander, Carl and Strömberg, Ulf LU (2020) In BMC Medical Research Methodology 20(1).
Abstract

Background: Selection and selection bias are terms that lack consistent definitions and have varying meaning and usage across disciplines. There is also confusion in current definitions between underlying mechanisms that lead to selection and their consequences. Consequences of selection on study validity must be judged on a case-by-case basis depending on research question, study design and analytical decisions. The overall aim of the study was to develop a simple but general framework for classifying various types of selection processes of relevance for epidemiological research. Methods: Several original articles from the epidemiological literature and from related areas of observational research were reviewed in search of examples of... (More)

Background: Selection and selection bias are terms that lack consistent definitions and have varying meaning and usage across disciplines. There is also confusion in current definitions between underlying mechanisms that lead to selection and their consequences. Consequences of selection on study validity must be judged on a case-by-case basis depending on research question, study design and analytical decisions. The overall aim of the study was to develop a simple but general framework for classifying various types of selection processes of relevance for epidemiological research. Methods: Several original articles from the epidemiological literature and from related areas of observational research were reviewed in search of examples of selection processes, used terminology and description of the underlying mechanisms. Results: We classified the identified selection processes in three dimensions: i) selection level (selection at the population level vs. study-specific selection), ii) type of mechanism (selection in exposure vs. selection in population composition), iii) timing of the selection (at exposure entry, during exposure/follow-up or post-outcome). Conclusions: Increased understanding of when, how, and why selection occur is an important step towards improved validity of epidemiological research.

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Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bias, Epidemiologic factors, Population characteristics, Public health, Selection bias
in
BMC Medical Research Methodology
volume
20
issue
1
article number
155
publisher
BioMed Central (BMC)
external identifiers
  • scopus:85086621661
  • pmid:32536343
ISSN
1471-2288
DOI
10.1186/s12874-020-01015-w
project
Nya statistiska ansatser för att bedöma betydelsen av selektion och variation i befolkningsbaserade kohort- och screeningundersökningar
language
English
LU publication?
yes
id
42eae197-3f19-4fb9-8f19-d66594ba8530
date added to LUP
2020-07-02 13:24:24
date last changed
2024-05-15 14:16:46
@article{42eae197-3f19-4fb9-8f19-d66594ba8530,
  abstract     = {{<p>Background: Selection and selection bias are terms that lack consistent definitions and have varying meaning and usage across disciplines. There is also confusion in current definitions between underlying mechanisms that lead to selection and their consequences. Consequences of selection on study validity must be judged on a case-by-case basis depending on research question, study design and analytical decisions. The overall aim of the study was to develop a simple but general framework for classifying various types of selection processes of relevance for epidemiological research. Methods: Several original articles from the epidemiological literature and from related areas of observational research were reviewed in search of examples of selection processes, used terminology and description of the underlying mechanisms. Results: We classified the identified selection processes in three dimensions: i) selection level (selection at the population level vs. study-specific selection), ii) type of mechanism (selection in exposure vs. selection in population composition), iii) timing of the selection (at exposure entry, during exposure/follow-up or post-outcome). Conclusions: Increased understanding of when, how, and why selection occur is an important step towards improved validity of epidemiological research.</p>}},
  author       = {{Björk, Jonas and Nilsson, Anton and Bonander, Carl and Strömberg, Ulf}},
  issn         = {{1471-2288}},
  keywords     = {{Bias; Epidemiologic factors; Population characteristics; Public health; Selection bias}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{BMC Medical Research Methodology}},
  title        = {{A novel framework for classification of selection processes in epidemiological research}},
  url          = {{http://dx.doi.org/10.1186/s12874-020-01015-w}},
  doi          = {{10.1186/s12874-020-01015-w}},
  volume       = {{20}},
  year         = {{2020}},
}