Advanced

Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.

Lehn, Sophie LU ; Tobin, Nicholas P LU ; Sims, Andrew H; Stål, Olle; Jirström, Karin LU ; Axelson, Håkan LU and Landberg, Göran LU (2014) In BMC Cancer 14(1).
Abstract
Yes-associated protein (YAP1) is frequently reported to function as an oncogene in many types of cancer, but in breast cancer results remain controversial. We set out to clarify the role of YAP1 in breast cancer by examining gene and protein expression in subgroups of patient material and by downregulating YAP1 in vitro and studying its role in response to the widely used anti-estrogen tamoxifen.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMC Cancer
volume
14
issue
1
publisher
BioMed Central
external identifiers
  • pmid:24559095
  • wos:000332526900002
  • scopus:84894668015
ISSN
1471-2407
DOI
10.1186/1471-2407-14-119
language
English
LU publication?
yes
id
dbbaedb4-e770-45a5-a850-63cead7f763e (old id 4334304)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24559095?dopt=Abstract
date added to LUP
2014-03-05 20:20:35
date last changed
2017-10-22 03:58:49
@article{dbbaedb4-e770-45a5-a850-63cead7f763e,
  abstract     = {Yes-associated protein (YAP1) is frequently reported to function as an oncogene in many types of cancer, but in breast cancer results remain controversial. We set out to clarify the role of YAP1 in breast cancer by examining gene and protein expression in subgroups of patient material and by downregulating YAP1 in vitro and studying its role in response to the widely used anti-estrogen tamoxifen.},
  articleno    = {119},
  author       = {Lehn, Sophie and Tobin, Nicholas P and Sims, Andrew H and Stål, Olle and Jirström, Karin and Axelson, Håkan and Landberg, Göran},
  issn         = {1471-2407},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {BMC Cancer},
  title        = {Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.},
  url          = {http://dx.doi.org/10.1186/1471-2407-14-119},
  volume       = {14},
  year         = {2014},
}