Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.
(2014) In BMC Cancer 14(1).- Abstract
- Yes-associated protein (YAP1) is frequently reported to function as an oncogene in many types of cancer, but in breast cancer results remain controversial. We set out to clarify the role of YAP1 in breast cancer by examining gene and protein expression in subgroups of patient material and by downregulating YAP1 in vitro and studying its role in response to the widely used anti-estrogen tamoxifen.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4334304
- author
- Lehn, Sophie
LU
; Tobin, Nicholas P
LU
; Sims, Andrew H
; Stål, Olle
; Jirström, Karin
LU
; Axelson, Håkan LU and Landberg, Göran LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Cancer
- volume
- 14
- issue
- 1
- article number
- 119
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:24559095
- wos:000332526900002
- scopus:84894668015
- pmid:24559095
- ISSN
- 1471-2407
- DOI
- 10.1186/1471-2407-14-119
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Molecular pathology (013031700), Pathology, (Lund) (013030000), Division of Translational Cancer Research (013250500), Pathology (Malmö) (013031000)
- id
- dbbaedb4-e770-45a5-a850-63cead7f763e (old id 4334304)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24559095?dopt=Abstract
- date added to LUP
- 2016-04-01 12:54:47
- date last changed
- 2024-01-09 04:49:55
@article{dbbaedb4-e770-45a5-a850-63cead7f763e, abstract = {{Yes-associated protein (YAP1) is frequently reported to function as an oncogene in many types of cancer, but in breast cancer results remain controversial. We set out to clarify the role of YAP1 in breast cancer by examining gene and protein expression in subgroups of patient material and by downregulating YAP1 in vitro and studying its role in response to the widely used anti-estrogen tamoxifen.}}, author = {{Lehn, Sophie and Tobin, Nicholas P and Sims, Andrew H and Stål, Olle and Jirström, Karin and Axelson, Håkan and Landberg, Göran}}, issn = {{1471-2407}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{BMC Cancer}}, title = {{Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.}}, url = {{https://lup.lub.lu.se/search/files/3043258/4693310.pdf}}, doi = {{10.1186/1471-2407-14-119}}, volume = {{14}}, year = {{2014}}, }