High plasma levels of islet amyloid polypeptide in young with new-onset of type 1 diabetes mellitus.
Paulsson, Johan F ; Ludvigsson, Johnny ; Carlsson, Annelie LU
; Casas, Rosaura
; Forsander, Gun
; Ivarsson, Sten
LU
; Kockum, Ingrid
; Lernmark, Åke
LU
; Marcus, Claude
and Lindblad, Bengt
LU
, et al.
(2014)
In PLoS ONE
9(3).
- Abstract
- Islet amyloid polypeptide (IAPP) is a beta cell hormone secreted together with insulin upon glucose stimulation. IAPP participates in normal glucose regulation, but IAPP is also known for its ability to misfold and form islet amyloid. Amyloid fibrils form through smaller cell toxic intermediates and deposited amyloid disrupts normal islet architecture. Even though IAPP and amyloid formation are much discussed in type 2 diabetes, our aim was to study the significance of IAPP in type 1 diabetes.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4379653
- author
- Paulsson, Johan F
; Ludvigsson, Johnny
; Carlsson, Annelie
LU
; Casas, Rosaura
; Forsander, Gun
; Ivarsson, Sten
LU
; Kockum, Ingrid
; Lernmark, Åke
LU
; Marcus, Claude
and Lindblad, Bengt
LU
, et al. (More)
- Paulsson, Johan F
; Ludvigsson, Johnny
; Carlsson, Annelie
LU
; Casas, Rosaura
; Forsander, Gun
; Ivarsson, Sten
LU
; Kockum, Ingrid
; Lernmark, Åke
LU
; Marcus, Claude
; Lindblad, Bengt
LU
and Westermark, Gunilla T
(Less)
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 9
- issue
- 3
- article number
- e93053
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- pmid:24671002
- wos:000333677000107
- scopus:84899802911
- pmid:24671002
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0093053
- project
- Better Diabetes Diagnosis (BDD)
- language
- English
- LU publication?
- yes
- id
- 3ab51cc1-919c-4f0e-a850-588702ebaee8 (old id 4379653)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24671002?dopt=Abstract
- date added to LUP
- 2016-04-01 14:28:48
- date last changed
- 2023-01-04 04:49:33
@article{3ab51cc1-919c-4f0e-a850-588702ebaee8,
abstract = {{Islet amyloid polypeptide (IAPP) is a beta cell hormone secreted together with insulin upon glucose stimulation. IAPP participates in normal glucose regulation, but IAPP is also known for its ability to misfold and form islet amyloid. Amyloid fibrils form through smaller cell toxic intermediates and deposited amyloid disrupts normal islet architecture. Even though IAPP and amyloid formation are much discussed in type 2 diabetes, our aim was to study the significance of IAPP in type 1 diabetes.}},
author = {{Paulsson, Johan F and Ludvigsson, Johnny and Carlsson, Annelie and Casas, Rosaura and Forsander, Gun and Ivarsson, Sten and Kockum, Ingrid and Lernmark, Åke and Marcus, Claude and Lindblad, Bengt and Westermark, Gunilla T}},
issn = {{1932-6203}},
language = {{eng}},
number = {{3}},
publisher = {{Public Library of Science (PLoS)}},
series = {{PLoS ONE}},
title = {{High plasma levels of islet amyloid polypeptide in young with new-onset of type 1 diabetes mellitus.}},
url = {{https://lup.lub.lu.se/search/files/3998864/4646878}},
doi = {{10.1371/journal.pone.0093053}},
volume = {{9}},
year = {{2014}},
}