Optimization of soft X-ray phase-contrast tomography using a laser wakefield accelerator
(2018) In Optics Express 26(26). p.33930-33941- Abstract
- X-ray phase-contrast imaging allows for non-invasive analysis in low-absorbing materials, such as soft tissue. Its application in medical or materials science has yet to be realized on a wider scale due to the requirements on the X-ray source, demanding high flux and small source size. Laser wakefield accelerators generate betatron X-rays fulfilling these criteria and can be suitable sources for phase-contrast imaging. In this work, we present the first phase-contrast images obtained by using ionization injection-based laser wakefield acceleration, which results in a higher photon yield and smoother X-ray beam profile compared to self-injection. A peak photon yield of 1.9 × 1011 ph/sr and a source size of 3 μm were estimated. Furthermore,... (More)
- X-ray phase-contrast imaging allows for non-invasive analysis in low-absorbing materials, such as soft tissue. Its application in medical or materials science has yet to be realized on a wider scale due to the requirements on the X-ray source, demanding high flux and small source size. Laser wakefield accelerators generate betatron X-rays fulfilling these criteria and can be suitable sources for phase-contrast imaging. In this work, we present the first phase-contrast images obtained by using ionization injection-based laser wakefield acceleration, which results in a higher photon yield and smoother X-ray beam profile compared to self-injection. A peak photon yield of 1.9 × 1011 ph/sr and a source size of 3 μm were estimated. Furthermore, the current laser parameters produce an X-ray spectrum mainly in the soft X-ray range, in which laser-plasma based phase-contrast imaging had yet to be studied. The phase-contrast images of a Chrysopa lacewing resolve features on the order of 4 μm. These images are further used for a tomographic reconstruction and a volume rendering, showing details on the order of tens of μm. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/43a84f38-a50e-4192-9f26-c8f6a136cc40
- author
- Svendsen, Kristoffer LU ; Gallardo Gonzalez, Isabel LU ; Hansson, Martin LU ; Björklund Svensson, Jonas LU ; Ekerfelt, Henrik LU ; Persson, Anders LU and Lundh, Olle LU
- organization
- publishing date
- 2018-12-24
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- betatron radiation, laser-wakefield acceleration, phase-contrast imaging
- in
- Optics Express
- volume
- 26
- issue
- 26
- pages
- 33930 - 33941
- publisher
- Optical Society of America
- external identifiers
-
- scopus:85059247778
- pmid:30650824
- ISSN
- 1094-4087
- DOI
- 10.1364/OE.26.033930
- project
- Extreme Electron Beams and Brilliant X-rays - Generation, Manipulation and Characterization of Relativistic Electron Beams for and from Plasma-Based Accelerators
- language
- English
- LU publication?
- yes
- id
- 43a84f38-a50e-4192-9f26-c8f6a136cc40
- date added to LUP
- 2018-12-17 18:05:09
- date last changed
- 2024-01-30 05:58:37
@article{43a84f38-a50e-4192-9f26-c8f6a136cc40, abstract = {{X-ray phase-contrast imaging allows for non-invasive analysis in low-absorbing materials, such as soft tissue. Its application in medical or materials science has yet to be realized on a wider scale due to the requirements on the X-ray source, demanding high flux and small source size. Laser wakefield accelerators generate betatron X-rays fulfilling these criteria and can be suitable sources for phase-contrast imaging. In this work, we present the first phase-contrast images obtained by using ionization injection-based laser wakefield acceleration, which results in a higher photon yield and smoother X-ray beam profile compared to self-injection. A peak photon yield of 1.9 × 1011 ph/sr and a source size of 3 μm were estimated. Furthermore, the current laser parameters produce an X-ray spectrum mainly in the soft X-ray range, in which laser-plasma based phase-contrast imaging had yet to be studied. The phase-contrast images of a Chrysopa lacewing resolve features on the order of 4 μm. These images are further used for a tomographic reconstruction and a volume rendering, showing details on the order of tens of μm.}}, author = {{Svendsen, Kristoffer and Gallardo Gonzalez, Isabel and Hansson, Martin and Björklund Svensson, Jonas and Ekerfelt, Henrik and Persson, Anders and Lundh, Olle}}, issn = {{1094-4087}}, keywords = {{betatron radiation; laser-wakefield acceleration; phase-contrast imaging}}, language = {{eng}}, month = {{12}}, number = {{26}}, pages = {{33930--33941}}, publisher = {{Optical Society of America}}, series = {{Optics Express}}, title = {{Optimization of soft X-ray phase-contrast tomography using a laser wakefield accelerator}}, url = {{http://dx.doi.org/10.1364/OE.26.033930}}, doi = {{10.1364/OE.26.033930}}, volume = {{26}}, year = {{2018}}, }