Impact of sex on perinatal mortality and morbidity in twins
(2014) In Journal of Perinatal Medicine 42(2). p.225-231- Abstract
- Objective: Twin studies offer opportunities to investigate mechanisms underlying sex-associated differences in perinatal outcomes. The objective of the study was to investigate sex-related differences in perinatal complications. Study design: A cohort of 16,045 twin pregnancies 32,090 twins - was explored for obstetric complications, perinatal and infant mortality, and neonatal morbidities. Results: Twin pregnancies with a female fetus had an increased risk for preeclampsia, but otherwise there were no pregnancy complications associated with fetal sex. After birth, female-female twins had lower early neonatal and infant mortality, and lower risk for respiratory morbidities than male-male twins at all gestational ages. In unlike-sexed twin... (More)
- Objective: Twin studies offer opportunities to investigate mechanisms underlying sex-associated differences in perinatal outcomes. The objective of the study was to investigate sex-related differences in perinatal complications. Study design: A cohort of 16,045 twin pregnancies 32,090 twins - was explored for obstetric complications, perinatal and infant mortality, and neonatal morbidities. Results: Twin pregnancies with a female fetus had an increased risk for preeclampsia, but otherwise there were no pregnancy complications associated with fetal sex. After birth, female-female twins had lower early neonatal and infant mortality, and lower risk for respiratory morbidities than male-male twins at all gestational ages. In unlike-sexed twin pairs, very preterm males had higher respiratory morbidity than females and, females were at higher risk for being growth restricted. Conclusion: Male-male twins have higher respiratory morbidity and neonatal mortality than female-female twins. In unliked-sexed twin pairs, the males seem to be protected by having a female co-twin. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4411082
- author
- Elsmén, Emma LU ; Källén, Karin LU ; Marsal, Karel LU ; Norman, Mikael and Hellstrom-Westas, Lena
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Growth restriction, newborn, respiratory morbidity, preeclampsia, preterm
- in
- Journal of Perinatal Medicine
- volume
- 42
- issue
- 2
- pages
- 225 - 231
- publisher
- De Gruyter
- external identifiers
-
- wos:000332843500011
- scopus:84898654897
- pmid:24222256
- ISSN
- 1619-3997
- DOI
- 10.1515/jpm-2013-0147
- language
- English
- LU publication?
- yes
- id
- 39712943-5ea7-455d-9d57-9bc57dc6f761 (old id 4411082)
- date added to LUP
- 2016-04-01 11:04:59
- date last changed
- 2022-01-26 05:10:55
@article{39712943-5ea7-455d-9d57-9bc57dc6f761, abstract = {{Objective: Twin studies offer opportunities to investigate mechanisms underlying sex-associated differences in perinatal outcomes. The objective of the study was to investigate sex-related differences in perinatal complications. Study design: A cohort of 16,045 twin pregnancies 32,090 twins - was explored for obstetric complications, perinatal and infant mortality, and neonatal morbidities. Results: Twin pregnancies with a female fetus had an increased risk for preeclampsia, but otherwise there were no pregnancy complications associated with fetal sex. After birth, female-female twins had lower early neonatal and infant mortality, and lower risk for respiratory morbidities than male-male twins at all gestational ages. In unlike-sexed twin pairs, very preterm males had higher respiratory morbidity than females and, females were at higher risk for being growth restricted. Conclusion: Male-male twins have higher respiratory morbidity and neonatal mortality than female-female twins. In unliked-sexed twin pairs, the males seem to be protected by having a female co-twin.}}, author = {{Elsmén, Emma and Källén, Karin and Marsal, Karel and Norman, Mikael and Hellstrom-Westas, Lena}}, issn = {{1619-3997}}, keywords = {{Growth restriction; newborn; respiratory morbidity; preeclampsia; preterm}}, language = {{eng}}, number = {{2}}, pages = {{225--231}}, publisher = {{De Gruyter}}, series = {{Journal of Perinatal Medicine}}, title = {{Impact of sex on perinatal mortality and morbidity in twins}}, url = {{https://lup.lub.lu.se/search/files/2368024/4759202.pdf}}, doi = {{10.1515/jpm-2013-0147}}, volume = {{42}}, year = {{2014}}, }