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Effects on heart rate variability by artificially generated indoor nano-sized particles in a chamber study

Hagerman, Inger; Isaxon, Christina LU ; Gudmundsson, Anders LU ; Wierzbicka, Aneta LU ; Dierschke, Katrin LU ; Berglund, Margareta; Pagels, Joakim LU ; Nielsen, Jörn LU ; Assarsson, Eva LU and Andersson, Ulla B LU , et al. (2014) In Atmospheric Environment 88. p.165-171
Abstract
Background: Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in nano-sized particles with diameter < 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups. Aim of study: The aim was to evaluate the impact of nano-sized indoor air particles on HRV for healthy and adult females. Methods: All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene + ozone reactions or filtered air in a double-blind cross over design. Twenty-two healthy females were investigated during... (More)
Background: Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in nano-sized particles with diameter < 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups. Aim of study: The aim was to evaluate the impact of nano-sized indoor air particles on HRV for healthy and adult females. Methods: All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene + ozone reactions or filtered air in a double-blind cross over design. Twenty-two healthy females were investigated during 10 min periods at different exposures and the reactivity in high frequency (HF) spectral band of HRV were computed. Results: Heart rate was unchanged from baseline values in all groups during all experimental settings. HF power of HRV tended to increase during exposure to particles from burning candle while particles from terpene + ozone reactions tended to decrease HF power. Conclusions: Exposure to nano-sized particles of burning candles or terpene + ozone reactions results in different patterns of heart rate variability, with signs of altered autonomic cardiovascular control. Practical implications: This study indicates that the HRV method may be used for information on physiological responses of exposure to different nano-sized particles and contribute to the understanding of mechanisms behind health effects of particle exposures. (C) 2014 The Authors. Published by Elsevier Ltd. (Less)
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subject
keywords
Airborne particles, Nano particles, HRV, Cardiovascular, Autonomic, control
in
Atmospheric Environment
volume
88
pages
165 - 171
publisher
Elsevier
external identifiers
  • wos:000335104300019
  • scopus:84894239621
ISSN
1352-2310
DOI
10.1016/j.atmosenv.2014.02.003
language
English
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yes
id
58790ae0-18f0-4fde-99e4-88f49fb6508f (old id 4482397)
date added to LUP
2014-07-01 07:36:09
date last changed
2017-11-19 04:01:42
@article{58790ae0-18f0-4fde-99e4-88f49fb6508f,
  abstract     = {Background: Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in nano-sized particles with diameter &lt; 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups. Aim of study: The aim was to evaluate the impact of nano-sized indoor air particles on HRV for healthy and adult females. Methods: All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene + ozone reactions or filtered air in a double-blind cross over design. Twenty-two healthy females were investigated during 10 min periods at different exposures and the reactivity in high frequency (HF) spectral band of HRV were computed. Results: Heart rate was unchanged from baseline values in all groups during all experimental settings. HF power of HRV tended to increase during exposure to particles from burning candle while particles from terpene + ozone reactions tended to decrease HF power. Conclusions: Exposure to nano-sized particles of burning candles or terpene + ozone reactions results in different patterns of heart rate variability, with signs of altered autonomic cardiovascular control. Practical implications: This study indicates that the HRV method may be used for information on physiological responses of exposure to different nano-sized particles and contribute to the understanding of mechanisms behind health effects of particle exposures. (C) 2014 The Authors. Published by Elsevier Ltd.},
  author       = {Hagerman, Inger and Isaxon, Christina and Gudmundsson, Anders and Wierzbicka, Aneta and Dierschke, Katrin and Berglund, Margareta and Pagels, Joakim and Nielsen, Jörn and Assarsson, Eva and Andersson, Ulla B and Xu, Yiyi and Jönsson, Bo A and Bohgard, Mats},
  issn         = {1352-2310},
  keyword      = {Airborne particles,Nano particles,HRV,Cardiovascular,Autonomic,control},
  language     = {eng},
  pages        = {165--171},
  publisher    = {Elsevier},
  series       = {Atmospheric Environment},
  title        = {Effects on heart rate variability by artificially generated indoor nano-sized particles in a chamber study},
  url          = {http://dx.doi.org/10.1016/j.atmosenv.2014.02.003},
  volume       = {88},
  year         = {2014},
}