Neuropeptide Y is a minor autoantigen in newly diagnosed type 1 diabetes patients.
Skärstrand, Hanna LU ; Vaziri Sani, Fariba LU ; Delli, Ahmed LU ; Törn, Carina LU ; Larsson, Helena LU ; Ivarsson, Sten LU ; Agardh, Daniel LU and Lernmark, Åke LU
(2015)
In Pediatric Diabetes
16(8).
p.621-628
- Abstract
- Autoantibodies (A) against Neuropeptide Y (NPY), was reported in 9% newly diagnosed type 1 diabetes (T1D) patients. A single nucleotide polymorphism (SNP) at rs16139 (T1128C) within the NPY-gene identified an amino acid substitution from leucine (L) to proline (P) (L7P) associated with both glucose tolerance and type 2 diabetes. We aimed to determine: (i) the influence of autoantibodies to leucine neuropeptide Y (NPY-LA) and autoantibodies to proline neuropeptide Y (NPY-PA) on the diagnostic sensitivity of type 1 diabetes (T1D), (ii) the association of NPYA with major islet autoantibodies, and (iii) the association of NPYA with HLA-DQ genotypes in newly diagnosed T1D patients.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4690890
- author
- Skärstrand, Hanna
LU
; Vaziri Sani, Fariba
LU
; Delli, Ahmed
LU
; Törn, Carina
LU
; Larsson, Helena
LU
; Ivarsson, Sten
LU
; Agardh, Daniel
LU
and Lernmark, Åke
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Pediatric Diabetes
- volume
- 16
- issue
- 8
- pages
- 621 - 628
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:25258030
- wos:000363929400009
- scopus:84946476107
- pmid:25258030
- ISSN
- 1399-543X
- DOI
- 10.1111/pedi.12222
- language
- English
- LU publication?
- yes
- id
- 4ee07cca-b889-4aea-8f18-aa024f6cd775 (old id 4690890)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25258030?dopt=Abstract
- date added to LUP
- 2016-04-01 10:33:33
- date last changed
- 2022-04-12 07:29:34
@article{4ee07cca-b889-4aea-8f18-aa024f6cd775,
abstract = {{Autoantibodies (A) against Neuropeptide Y (NPY), was reported in 9% newly diagnosed type 1 diabetes (T1D) patients. A single nucleotide polymorphism (SNP) at rs16139 (T1128C) within the NPY-gene identified an amino acid substitution from leucine (L) to proline (P) (L7P) associated with both glucose tolerance and type 2 diabetes. We aimed to determine: (i) the influence of autoantibodies to leucine neuropeptide Y (NPY-LA) and autoantibodies to proline neuropeptide Y (NPY-PA) on the diagnostic sensitivity of type 1 diabetes (T1D), (ii) the association of NPYA with major islet autoantibodies, and (iii) the association of NPYA with HLA-DQ genotypes in newly diagnosed T1D patients.}},
author = {{Skärstrand, Hanna and Vaziri Sani, Fariba and Delli, Ahmed and Törn, Carina and Larsson, Helena and Ivarsson, Sten and Agardh, Daniel and Lernmark, Åke}},
issn = {{1399-543X}},
language = {{eng}},
number = {{8}},
pages = {{621--628}},
publisher = {{Wiley-Blackwell}},
series = {{Pediatric Diabetes}},
title = {{Neuropeptide Y is a minor autoantigen in newly diagnosed type 1 diabetes patients.}},
url = {{http://dx.doi.org/10.1111/pedi.12222}},
doi = {{10.1111/pedi.12222}},
volume = {{16}},
year = {{2015}},
}