Evaluation of Algorithms for the Treatment of Problem Bleeding Episodes in Patients With Hemophilia Having Inhibitors.
(2015) In Clinical and Applied Thrombosis/Hemostasis 21(1). p.10-18- Abstract
- The correlation between real-world clinical decisions and adherence to published treatment algorithms for problem bleeding episodes in patients with severe hemophilia and inhibitors and the resultant impact on clinical outcomes were assessed. Nine cases documenting treatment for problem bleeding episodes in patients with severe hemophilia and inhibitors were retrospectively reviewed. Adherence to treatment algorithms was rated on a scale of 1 to 5, 1 being no adherence and 5 being very high adherence. Adherence ratings >3 were assigned to 7 cases in which high adherence was associated with ≤4 days to achieve hemostatic control; hospitalization for ≤7 days was noted in 6 of these cases. In cases rated ≤3 (n = 2), time to hemostatic... (More)
- The correlation between real-world clinical decisions and adherence to published treatment algorithms for problem bleeding episodes in patients with severe hemophilia and inhibitors and the resultant impact on clinical outcomes were assessed. Nine cases documenting treatment for problem bleeding episodes in patients with severe hemophilia and inhibitors were retrospectively reviewed. Adherence to treatment algorithms was rated on a scale of 1 to 5, 1 being no adherence and 5 being very high adherence. Adherence ratings >3 were assigned to 7 cases in which high adherence was associated with ≤4 days to achieve hemostatic control; hospitalization for ≤7 days was noted in 6 of these cases. In cases rated ≤3 (n = 2), time to hemostatic control ranged from 5 to 8 days and hospitalization duration ranged from 10 to 16 days. These findings suggest that adherence to treatment algorithms may be beneficial in treating problem bleeding events in patients with hemophilia and inhibitors. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4733282
- author
- Young, Guy ; Teitel, Jerome ; d'Oiron, Roseline ; Leissinger, Cindy and Berntorp, Erik LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical and Applied Thrombosis/Hemostasis
- volume
- 21
- issue
- 1
- pages
- 10 - 18
- publisher
- SAGE Publications
- external identifiers
-
- pmid:25343956
- wos:000345894700002
- scopus:84914146074
- pmid:25343956
- ISSN
- 1938-2723
- DOI
- 10.1177/1076029614554993
- language
- English
- LU publication?
- yes
- id
- e602a20b-a947-4f5d-99c4-6020d11f5868 (old id 4733282)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25343956?dopt=Abstract
- date added to LUP
- 2016-04-01 11:06:04
- date last changed
- 2022-01-26 05:22:03
@article{e602a20b-a947-4f5d-99c4-6020d11f5868,
abstract = {{The correlation between real-world clinical decisions and adherence to published treatment algorithms for problem bleeding episodes in patients with severe hemophilia and inhibitors and the resultant impact on clinical outcomes were assessed. Nine cases documenting treatment for problem bleeding episodes in patients with severe hemophilia and inhibitors were retrospectively reviewed. Adherence to treatment algorithms was rated on a scale of 1 to 5, 1 being no adherence and 5 being very high adherence. Adherence ratings >3 were assigned to 7 cases in which high adherence was associated with ≤4 days to achieve hemostatic control; hospitalization for ≤7 days was noted in 6 of these cases. In cases rated ≤3 (n = 2), time to hemostatic control ranged from 5 to 8 days and hospitalization duration ranged from 10 to 16 days. These findings suggest that adherence to treatment algorithms may be beneficial in treating problem bleeding events in patients with hemophilia and inhibitors.}},
author = {{Young, Guy and Teitel, Jerome and d'Oiron, Roseline and Leissinger, Cindy and Berntorp, Erik}},
issn = {{1938-2723}},
language = {{eng}},
number = {{1}},
pages = {{10--18}},
publisher = {{SAGE Publications}},
series = {{Clinical and Applied Thrombosis/Hemostasis}},
title = {{Evaluation of Algorithms for the Treatment of Problem Bleeding Episodes in Patients With Hemophilia Having Inhibitors.}},
url = {{http://dx.doi.org/10.1177/1076029614554993}},
doi = {{10.1177/1076029614554993}},
volume = {{21}},
year = {{2015}},
}