Risks of papillary and follicular thyroid cancer among immigrants to Sweden
(2011) In International Journal of Cancer 129(9). p.2248-2255- Abstract
- Previous studies have indicated that ionizing radiation, particularly during childhood, is the main established risk factor for thyroid cancer. History of benign nodules/adenoma, goiter, iodine deficiency or high-iodine intake might be other associated factors. We wanted to define the histology-specific thyroid cancer risk in the first-generation immigrants to Sweden. We used the 2010 update of the nation-wide Swedish Family-Cancer Database (>12 million individuals; 1.8 million immigrants; histology code in force since 1958) to calculate standardized incidence ratios (SIRs) for histology-specific thyroid cancer among immigrants compared to the native Swedes. The patient series covered 2,604 male and 6,406 female Swedes, and 247 and 863... (More)
- Previous studies have indicated that ionizing radiation, particularly during childhood, is the main established risk factor for thyroid cancer. History of benign nodules/adenoma, goiter, iodine deficiency or high-iodine intake might be other associated factors. We wanted to define the histology-specific thyroid cancer risk in the first-generation immigrants to Sweden. We used the 2010 update of the nation-wide Swedish Family-Cancer Database (>12 million individuals; 1.8 million immigrants; histology code in force since 1958) to calculate standardized incidence ratios (SIRs) for histology-specific thyroid cancer among immigrants compared to the native Swedes. The patient series covered 2,604 male and 6,406 female Swedes, and 247 and 863 immigrants. The median age at immigration was 29 years, and the median age at thyroid cancer diagnosis was 46 years. Increased risks for female papillary carcinoma were observed for Finns (SIR = 1.63), former Yugoslavians (2.36), Russians (2.34), other East Europeans (2.14), Turks (3.16), Iranians (2.68), Iraqis (2.77), East and Southeast Asians (2.92), other Asians (1.69) and South Americans (2.23). Male Iranians (2.85), East and Southeast Asians (3.57) and other Asians (2.26) had an increased risk for papillary carcinoma. Only male East and Southeast Asians (2.93) had an increased risk for follicular carcinoma. The data might suggest that immigrant populations in Sweden from areas of low or high-iodine intake are at risk of papillary carcinoma, implicating iodine imbalance as a contributing factor to our findings. The increased risk of thyroid cancer among Asian immigrants may confirm the role of childhood-ionizing radiation on thyroid cancer risk. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2179888
- author
- Mousavi, Seyed Mohsen ; Brandt, Andreas ; Sundquist, Jan LU and Hemminki, Kari LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- follicular carcinoma, iodine salt, papillary carcinoma, risk, thyroid, cancer
- in
- International Journal of Cancer
- volume
- 129
- issue
- 9
- pages
- 2248 - 2255
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000295230500019
- scopus:80052196818
- pmid:21170937
- ISSN
- 0020-7136
- DOI
- 10.1002/ijc.25867
- language
- English
- LU publication?
- yes
- id
- 47cf4c25-b849-4acf-8276-7cad9a8baf01 (old id 2179888)
- date added to LUP
- 2016-04-01 11:07:29
- date last changed
- 2022-01-26 05:38:52
@article{47cf4c25-b849-4acf-8276-7cad9a8baf01,
abstract = {{Previous studies have indicated that ionizing radiation, particularly during childhood, is the main established risk factor for thyroid cancer. History of benign nodules/adenoma, goiter, iodine deficiency or high-iodine intake might be other associated factors. We wanted to define the histology-specific thyroid cancer risk in the first-generation immigrants to Sweden. We used the 2010 update of the nation-wide Swedish Family-Cancer Database (>12 million individuals; 1.8 million immigrants; histology code in force since 1958) to calculate standardized incidence ratios (SIRs) for histology-specific thyroid cancer among immigrants compared to the native Swedes. The patient series covered 2,604 male and 6,406 female Swedes, and 247 and 863 immigrants. The median age at immigration was 29 years, and the median age at thyroid cancer diagnosis was 46 years. Increased risks for female papillary carcinoma were observed for Finns (SIR = 1.63), former Yugoslavians (2.36), Russians (2.34), other East Europeans (2.14), Turks (3.16), Iranians (2.68), Iraqis (2.77), East and Southeast Asians (2.92), other Asians (1.69) and South Americans (2.23). Male Iranians (2.85), East and Southeast Asians (3.57) and other Asians (2.26) had an increased risk for papillary carcinoma. Only male East and Southeast Asians (2.93) had an increased risk for follicular carcinoma. The data might suggest that immigrant populations in Sweden from areas of low or high-iodine intake are at risk of papillary carcinoma, implicating iodine imbalance as a contributing factor to our findings. The increased risk of thyroid cancer among Asian immigrants may confirm the role of childhood-ionizing radiation on thyroid cancer risk.}},
author = {{Mousavi, Seyed Mohsen and Brandt, Andreas and Sundquist, Jan and Hemminki, Kari}},
issn = {{0020-7136}},
keywords = {{follicular carcinoma; iodine salt; papillary carcinoma; risk; thyroid; cancer}},
language = {{eng}},
number = {{9}},
pages = {{2248--2255}},
publisher = {{John Wiley & Sons Inc.}},
series = {{International Journal of Cancer}},
title = {{Risks of papillary and follicular thyroid cancer among immigrants to Sweden}},
url = {{http://dx.doi.org/10.1002/ijc.25867}},
doi = {{10.1002/ijc.25867}},
volume = {{129}},
year = {{2011}},
}