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Soft-tissue sarcomas and exposure to chemical substances : A case-referent study

Eriksson, M. LU orcid ; Hardell, L. ; Berg, N. O. ; Möller, T. LU and Axelson, O. (1981) In British Journal of Industrial Medicine 38(1). p.27-33
Abstract

In 1977 several patients were seen with soft-tissue sarcomas and previous exposure to phenoxy acids. This clinical observation resulted in a case-referent (case-control) study being undertaken which showed that exposure to phenoxy acids or chlorophenols, which are chemically related, gave a roughly six-fold increase in the risk for this type of tumor. A further case-referent study of soft-tissue sarcomas has now been performed to confirm these earlier findings and also to obtain further information on the effects of different phenoxy acids. This new investigation gave an increase of the same magnitude in the risk for soft-tissue sarcomas after exposure to phenoxy acids or chlorophenols, but this risk related also to exposure to phenoxy... (More)

In 1977 several patients were seen with soft-tissue sarcomas and previous exposure to phenoxy acids. This clinical observation resulted in a case-referent (case-control) study being undertaken which showed that exposure to phenoxy acids or chlorophenols, which are chemically related, gave a roughly six-fold increase in the risk for this type of tumor. A further case-referent study of soft-tissue sarcomas has now been performed to confirm these earlier findings and also to obtain further information on the effects of different phenoxy acids. This new investigation gave an increase of the same magnitude in the risk for soft-tissue sarcomas after exposure to phenoxy acids or chlorophenols, but this risk related also to exposure to phenoxy acids free from impurities, such as polychlorinated dibenzodioxins and dibenzofurans.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Industrial Medicine
volume
38
issue
1
pages
27 - 33
publisher
BMJ Publishing Group
external identifiers
  • pmid:7470401
  • scopus:0019514325
ISSN
0007-1072
DOI
10.1136/oem.38.1.27
language
English
LU publication?
yes
id
480a4f21-f712-4f5a-8e14-2ce1819c4139
date added to LUP
2020-03-23 16:22:50
date last changed
2024-01-02 07:35:39
@article{480a4f21-f712-4f5a-8e14-2ce1819c4139,
  abstract     = {{<p>In 1977 several patients were seen with soft-tissue sarcomas and previous exposure to phenoxy acids. This clinical observation resulted in a case-referent (case-control) study being undertaken which showed that exposure to phenoxy acids or chlorophenols, which are chemically related, gave a roughly six-fold increase in the risk for this type of tumor. A further case-referent study of soft-tissue sarcomas has now been performed to confirm these earlier findings and also to obtain further information on the effects of different phenoxy acids. This new investigation gave an increase of the same magnitude in the risk for soft-tissue sarcomas after exposure to phenoxy acids or chlorophenols, but this risk related also to exposure to phenoxy acids free from impurities, such as polychlorinated dibenzodioxins and dibenzofurans.</p>}},
  author       = {{Eriksson, M. and Hardell, L. and Berg, N. O. and Möller, T. and Axelson, O.}},
  issn         = {{0007-1072}},
  language     = {{eng}},
  month        = {{05}},
  number       = {{1}},
  pages        = {{27--33}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{British Journal of Industrial Medicine}},
  title        = {{Soft-tissue sarcomas and exposure to chemical substances : A case-referent study}},
  url          = {{http://dx.doi.org/10.1136/oem.38.1.27}},
  doi          = {{10.1136/oem.38.1.27}},
  volume       = {{38}},
  year         = {{1981}},
}