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Mindfulness group therapy in primary care patients with depression, anxiety and stress and adjustment disorders: randomised controlled trial.

Sundquist, Jan LU ; Lilja, Åsa LU ; Palmér, Karolina LU ; Memon, Ashfaque LU orcid ; Wang, Xiao LU ; Johansson, Leena Maria LU and Sundquist, Kristina LU (2015) In British Journal of Psychiatry 206(2). p.128-135
Abstract
Background Individual-based cognitive-behavioural therapy (CBT) is in short supply and expensive. Aims The aim of this randomised controlled trial (RCT) was to compare mindfulness-based group therapy with treatment as usual (primarily individual-based CBT) in primary care patients with depressive, anxiety or stress and adjustment disorders. Method This 8-week RCT (ClinicalTrials.gov ID: NCT01476371) was conducted during spring 2012 at 16 general practices in Southern Sweden. Eligible patients (aged 20-64 years) scored ⩾10 on the Patient Health Questionnaire-9, ⩾7 on the Hospital Anxiety and Depression Scale or 13-34 on the Montgomery-Åsberg Depression Rating Scale (self-rated version). The power calculations were based on non-inferiority.... (More)
Background Individual-based cognitive-behavioural therapy (CBT) is in short supply and expensive. Aims The aim of this randomised controlled trial (RCT) was to compare mindfulness-based group therapy with treatment as usual (primarily individual-based CBT) in primary care patients with depressive, anxiety or stress and adjustment disorders. Method This 8-week RCT (ClinicalTrials.gov ID: NCT01476371) was conducted during spring 2012 at 16 general practices in Southern Sweden. Eligible patients (aged 20-64 years) scored ⩾10 on the Patient Health Questionnaire-9, ⩾7 on the Hospital Anxiety and Depression Scale or 13-34 on the Montgomery-Åsberg Depression Rating Scale (self-rated version). The power calculations were based on non-inferiority. In total, 215 patients were randomised. Ordinal mixed models were used for the analysis. Results For all scales and in both groups, the scores decreased significantly. There were no significant differences between the mindfulness and control groups. Conclusions Mindfulness-based group therapy was non-inferior to treatment as usual for patients with depressive, anxiety or stress and adjustment disorders. (Less)
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Psychiatry
volume
206
issue
2
pages
128 - 135
publisher
Cambridge University Press
external identifiers
  • pmid:25431430
  • wos:000349277100008
  • scopus:84923013568
  • pmid:25431430
ISSN
0007-1250
DOI
10.1192/bjp.bp.114.150243
project
Molecular mechanism associated with response to psychotherapeutic interventions in patients with depression/anxiety in primary care patients
language
English
LU publication?
yes
id
95abc3d5-891e-470c-886c-19dd98428a4b (old id 4815821)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25431430?dopt=Abstract
date added to LUP
2016-04-01 11:07:33
date last changed
2022-04-20 17:11:38
@article{95abc3d5-891e-470c-886c-19dd98428a4b,
  abstract     = {{Background Individual-based cognitive-behavioural therapy (CBT) is in short supply and expensive. Aims The aim of this randomised controlled trial (RCT) was to compare mindfulness-based group therapy with treatment as usual (primarily individual-based CBT) in primary care patients with depressive, anxiety or stress and adjustment disorders. Method This 8-week RCT (ClinicalTrials.gov ID: NCT01476371) was conducted during spring 2012 at 16 general practices in Southern Sweden. Eligible patients (aged 20-64 years) scored ⩾10 on the Patient Health Questionnaire-9, ⩾7 on the Hospital Anxiety and Depression Scale or 13-34 on the Montgomery-Åsberg Depression Rating Scale (self-rated version). The power calculations were based on non-inferiority. In total, 215 patients were randomised. Ordinal mixed models were used for the analysis. Results For all scales and in both groups, the scores decreased significantly. There were no significant differences between the mindfulness and control groups. Conclusions Mindfulness-based group therapy was non-inferior to treatment as usual for patients with depressive, anxiety or stress and adjustment disorders.}},
  author       = {{Sundquist, Jan and Lilja, Åsa and Palmér, Karolina and Memon, Ashfaque and Wang, Xiao and Johansson, Leena Maria and Sundquist, Kristina}},
  issn         = {{0007-1250}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{128--135}},
  publisher    = {{Cambridge University Press}},
  series       = {{British Journal of Psychiatry}},
  title        = {{Mindfulness group therapy in primary care patients with depression, anxiety and stress and adjustment disorders: randomised controlled trial.}},
  url          = {{http://dx.doi.org/10.1192/bjp.bp.114.150243}},
  doi          = {{10.1192/bjp.bp.114.150243}},
  volume       = {{206}},
  year         = {{2015}},
}