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Consumption of fatty foods and incident type 2 diabetes in populations from eight European countries.

Buijsse, B; Boeing, H; Drogan, D; Schulze, M B; Feskens, E J; Amiano, P; Barricarte, A; Clavel-Chapelon, F; de Lauzon-Guillain, B and Fagherazzi, G, et al. (2015) In European Journal of Clinical Nutrition 69(4). p.455-461
Abstract
Background/Objectives:Diets high in saturated and trans fat and low in unsaturated fat may increase type 2 diabetes (T2D) risk, but studies on foods high in fat per unit weight are sparse. We assessed whether the intake of vegetable oil, butter, margarine, nuts and seeds and cakes and cookies is related to incident T2D.Subjects/Methods:A case-cohort study was conducted, nested within eight countries of the European Prospective Investigation into Cancer (EPIC), with 12 403 incident T2D cases and a subcohort of 16 835 people, identified from a cohort of 340 234 people. Diet was assessed at baseline (1991-1999) by country-specific questionnaires. Country-specific hazard ratios (HRs) across four categories of fatty foods (nonconsumers and... (More)
Background/Objectives:Diets high in saturated and trans fat and low in unsaturated fat may increase type 2 diabetes (T2D) risk, but studies on foods high in fat per unit weight are sparse. We assessed whether the intake of vegetable oil, butter, margarine, nuts and seeds and cakes and cookies is related to incident T2D.Subjects/Methods:A case-cohort study was conducted, nested within eight countries of the European Prospective Investigation into Cancer (EPIC), with 12 403 incident T2D cases and a subcohort of 16 835 people, identified from a cohort of 340 234 people. Diet was assessed at baseline (1991-1999) by country-specific questionnaires. Country-specific hazard ratios (HRs) across four categories of fatty foods (nonconsumers and tertiles among consumers) were combined with random-effects meta-analysis.Results:After adjustment not including body mass index (BMI), nonconsumers of butter, nuts and seeds and cakes and cookies were at higher T2D risk compared with the middle tertile of consumption. Among consumers, cakes and cookies were inversely related to T2D (HRs across increasing tertiles 1.14, 1.00 and 0.92, respectively; P-trend <0.0001). All these associations attenuated upon adjustment for BMI, except the higher risk of nonconsumers of cakes and cookies (HR 1.57). Higher consumption of margarine became positively associated after BMI adjustment (HRs across increasing consumption tertiles: 0.93, 1.00 and 1.12; P-trend 0.03). Within consumers, vegetable oil, butter and nuts and seeds were unrelated to T2D.Conclusions:Fatty foods were generally not associated with T2D, apart from weak positive association for margarine. The higher risk among nonconsumers of cakes and cookies needs further explanation.European Journal of Clinical Nutrition advance online publication, 26 November 2014; doi:10.1038/ejcn.2014.249. (Less)
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European Journal of Clinical Nutrition
volume
69
issue
4
pages
455 - 461
publisher
Nature Publishing Group
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  • pmid:25424603
  • wos:000352216300008
  • scopus:84926418601
ISSN
1476-5640
DOI
10.1038/ejcn.2014.249
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English
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yes
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27a620c9-af80-480f-a9ba-67e861670b9a (old id 4815998)
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http://www.ncbi.nlm.nih.gov/pubmed/25424603?dopt=Abstract
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2014-12-06 20:15:08
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2017-07-23 03:27:51
@article{27a620c9-af80-480f-a9ba-67e861670b9a,
  abstract     = {Background/Objectives:Diets high in saturated and trans fat and low in unsaturated fat may increase type 2 diabetes (T2D) risk, but studies on foods high in fat per unit weight are sparse. We assessed whether the intake of vegetable oil, butter, margarine, nuts and seeds and cakes and cookies is related to incident T2D.Subjects/Methods:A case-cohort study was conducted, nested within eight countries of the European Prospective Investigation into Cancer (EPIC), with 12 403 incident T2D cases and a subcohort of 16 835 people, identified from a cohort of 340 234 people. Diet was assessed at baseline (1991-1999) by country-specific questionnaires. Country-specific hazard ratios (HRs) across four categories of fatty foods (nonconsumers and tertiles among consumers) were combined with random-effects meta-analysis.Results:After adjustment not including body mass index (BMI), nonconsumers of butter, nuts and seeds and cakes and cookies were at higher T2D risk compared with the middle tertile of consumption. Among consumers, cakes and cookies were inversely related to T2D (HRs across increasing tertiles 1.14, 1.00 and 0.92, respectively; P-trend &lt;0.0001). All these associations attenuated upon adjustment for BMI, except the higher risk of nonconsumers of cakes and cookies (HR 1.57). Higher consumption of margarine became positively associated after BMI adjustment (HRs across increasing consumption tertiles: 0.93, 1.00 and 1.12; P-trend 0.03). Within consumers, vegetable oil, butter and nuts and seeds were unrelated to T2D.Conclusions:Fatty foods were generally not associated with T2D, apart from weak positive association for margarine. The higher risk among nonconsumers of cakes and cookies needs further explanation.European Journal of Clinical Nutrition advance online publication, 26 November 2014; doi:10.1038/ejcn.2014.249.},
  author       = {Buijsse, B and Boeing, H and Drogan, D and Schulze, M B and Feskens, E J and Amiano, P and Barricarte, A and Clavel-Chapelon, F and de Lauzon-Guillain, B and Fagherazzi, G and Fonseca-Nunes, A and Franks, Paul and Huerta, J M and Jakobsen, M U and Kaaks, R and Key, T J and Khaw, K T and Masala, G and Moskal, A and Nilsson, Peter and Overvad, K and Pala, V and Panico, S and Redondo, M L and Ricceri, F and Rolandsson, O and Sánchez, M-J and Sluijs, I and Spijkerman, A M and Tjonneland, A and Tumino, R and van der A, D L and van der Schouw, Y T and Langenberg, C and Sharp, S J and Forouhi, N G and Riboli, E and Wareham, N J},
  issn         = {1476-5640},
  language     = {eng},
  number       = {4},
  pages        = {455--461},
  publisher    = {Nature Publishing Group},
  series       = {European Journal of Clinical Nutrition},
  title        = {Consumption of fatty foods and incident type 2 diabetes in populations from eight European countries.},
  url          = {http://dx.doi.org/10.1038/ejcn.2014.249},
  volume       = {69},
  year         = {2015},
}