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Vitamin D and probiotics supplement use in young children with genetic risk for type 1 diabetes

Yang, J.; Tamura, R. N.; Uusitalo, U. M.; Aronsson, C. A. LU ; Silvis, K.; Riikonen, A.; Frank, N.; Joslowski, G.; Winkler, C. and Norris, J. M., et al. (2017) In European Journal of Clinical Nutrition 71(12). p.1449-1454
Abstract

Background/Objectives:Vitamin D and probiotics are nutrients of interest in the context of type 1 diabetes (T1D). We assessed the prevalence of and factors associated with vitamin D and probiotic supplementations among young children with genetic risk of T1D.Subjects/Methods:Use of supplements during the first 2 years of life was collected prospectively from 8674 children in The Environmental Determinants of Diabetes in the Young (TEDDY) study.Results:Single and/or multivitamin/mineral (MVM) supplements were reported by 81% of the children. The majority of participants in Finland, Germany and Sweden (97-99%) and 50% in the United States received vitamin D supplements that were mostly MVMs. Probiotics use varied from 6% in the United... (More)

Background/Objectives:Vitamin D and probiotics are nutrients of interest in the context of type 1 diabetes (T1D). We assessed the prevalence of and factors associated with vitamin D and probiotic supplementations among young children with genetic risk of T1D.Subjects/Methods:Use of supplements during the first 2 years of life was collected prospectively from 8674 children in The Environmental Determinants of Diabetes in the Young (TEDDY) study.Results:Single and/or multivitamin/mineral (MVM) supplements were reported by 81% of the children. The majority of participants in Finland, Germany and Sweden (97-99%) and 50% in the United States received vitamin D supplements that were mostly MVMs. Probiotics use varied from 6% in the United States to 60% in Finland and was primarily from probiotics-only preparations. More than 80% of the vitamin D and probiotics supplementation was initiated during infancy, and more than half of the uses lasted longer than a year. Being the first child, longer duration of breastfeeding, born in a later year, older maternal age and higher maternal education level were associated with both vitamin D and probiotics use. Shorter gestational age and mother not smoking during pregnancy were associated with a higher likelihood of probiotics supplementation only.Conclusions:Vitamin D and probiotics supplementations are popular in children 0-2 years old and are associated with common factors. Data documented here will allow evaluation of the relationship between early childhood dietary intake and the development of islet autoimmunity and progression to T1D.

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Contribution to journal
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published
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European Journal of Clinical Nutrition
volume
71
issue
12
pages
1449 - 1454
publisher
Nature Publishing Group
external identifiers
  • scopus:85042719404
ISSN
0954-3007
DOI
10.1038/ejcn.2017.140
language
English
LU publication?
yes
id
49868b7d-e463-4da9-b13a-bdbc794e681a
alternative location
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718924/
date added to LUP
2018-03-23 13:12:03
date last changed
2019-11-13 05:04:07
@article{49868b7d-e463-4da9-b13a-bdbc794e681a,
  abstract     = {<p>Background/Objectives:Vitamin D and probiotics are nutrients of interest in the context of type 1 diabetes (T1D). We assessed the prevalence of and factors associated with vitamin D and probiotic supplementations among young children with genetic risk of T1D.Subjects/Methods:Use of supplements during the first 2 years of life was collected prospectively from 8674 children in The Environmental Determinants of Diabetes in the Young (TEDDY) study.Results:Single and/or multivitamin/mineral (MVM) supplements were reported by 81% of the children. The majority of participants in Finland, Germany and Sweden (97-99%) and 50% in the United States received vitamin D supplements that were mostly MVMs. Probiotics use varied from 6% in the United States to 60% in Finland and was primarily from probiotics-only preparations. More than 80% of the vitamin D and probiotics supplementation was initiated during infancy, and more than half of the uses lasted longer than a year. Being the first child, longer duration of breastfeeding, born in a later year, older maternal age and higher maternal education level were associated with both vitamin D and probiotics use. Shorter gestational age and mother not smoking during pregnancy were associated with a higher likelihood of probiotics supplementation only.Conclusions:Vitamin D and probiotics supplementations are popular in children 0-2 years old and are associated with common factors. Data documented here will allow evaluation of the relationship between early childhood dietary intake and the development of islet autoimmunity and progression to T1D.</p>},
  author       = {Yang, J. and Tamura, R. N. and Uusitalo, U. M. and Aronsson, C. A. and Silvis, K. and Riikonen, A. and Frank, N. and Joslowski, G. and Winkler, C. and Norris, J. M. and Virtanen, S. M. and , },
  issn         = {0954-3007},
  language     = {eng},
  month        = {12},
  number       = {12},
  pages        = {1449--1454},
  publisher    = {Nature Publishing Group},
  series       = {European Journal of Clinical Nutrition},
  title        = {Vitamin D and probiotics supplement use in young children with genetic risk for type 1 diabetes},
  url          = {http://dx.doi.org/10.1038/ejcn.2017.140},
  volume       = {71},
  year         = {2017},
}