Generation of a human induced pluripotent stem cell line (CSC-42) from a patient with sporadic form of Parkinson's disease
Savchenko, Ekaterina LU ; Marote, Ana LU ; Russ, Kaspar LU ; Collin, Anna LU ; Goldwurm, Stefano ; Roybon, Laurent LU and Pomeshchik, Yuriy LU
(2018)
In Stem Cell Research
27.
p.78-81
- Abstract
Skin fibroblasts were collected from a 44-year-old patient with sporadic case of Parkinson's disease (PD). The non-integrating Sendai virus vector encoding OCT3/4, SOX2, c-MYC and KLF4 was used to reprogram fibroblasts into induced pluripotent stem cells (iPSCs). Generated iPSCs had normal karyotypes, expressed common stem cell markers, and were capable of differentiating into all three germ layers. Generated line could be used for PD modeling to understand the mechanisms that influence the disorder.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4a46a736-36f8-4bea-b3e0-1da986bbbd70
- author
- Savchenko, Ekaterina
LU
; Marote, Ana
LU
; Russ, Kaspar
LU
; Collin, Anna
LU
; Goldwurm, Stefano
; Roybon, Laurent
LU
and Pomeshchik, Yuriy
LU
- organization
- publishing date
- 2018-03-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Stem Cell Research
- volume
- 27
- pages
- 4 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:29334629
- scopus:85040374604
- ISSN
- 1873-5061
- DOI
- 10.1016/j.scr.2018.01.002
- language
- English
- LU publication?
- yes
- id
- 4a46a736-36f8-4bea-b3e0-1da986bbbd70
- date added to LUP
- 2018-01-22 09:00:17
- date last changed
- 2024-03-31 23:48:40
@article{4a46a736-36f8-4bea-b3e0-1da986bbbd70,
abstract = {{<p>Skin fibroblasts were collected from a 44-year-old patient with sporadic case of Parkinson's disease (PD). The non-integrating Sendai virus vector encoding OCT3/4, SOX2, c-MYC and KLF4 was used to reprogram fibroblasts into induced pluripotent stem cells (iPSCs). Generated iPSCs had normal karyotypes, expressed common stem cell markers, and were capable of differentiating into all three germ layers. Generated line could be used for PD modeling to understand the mechanisms that influence the disorder.</p>}},
author = {{Savchenko, Ekaterina and Marote, Ana and Russ, Kaspar and Collin, Anna and Goldwurm, Stefano and Roybon, Laurent and Pomeshchik, Yuriy}},
issn = {{1873-5061}},
language = {{eng}},
month = {{03}},
pages = {{78--81}},
publisher = {{Elsevier}},
series = {{Stem Cell Research}},
title = {{Generation of a human induced pluripotent stem cell line (CSC-42) from a patient with sporadic form of Parkinson's disease}},
url = {{http://dx.doi.org/10.1016/j.scr.2018.01.002}},
doi = {{10.1016/j.scr.2018.01.002}},
volume = {{27}},
year = {{2018}},
}