Severe Acute Pancreatitis - Outcome following a Primarily Non-Surgical Regime.
Andersson, Bodil LU
; Olin, Hanna
; Eckerwall, Gunilla
LU
and Andersson, Roland
LU
(2006)
In Pancreatology
6(6).
p.536-541
- Abstract
- Background/Aims: Severe acute pancreatitis ( SAP) is associated with a high morbidity and mortality. The aim was to evaluate treatment, risk factors and outcome in SAP in a centre with a restrictive attitude to surgery. Methods: All cases of acute pancreatitis admitted 1994 - 2003 were analysed retrospectively. SAP was defined as organ failure and/or hospital stay > 7 days together with one or more of: C-reactive protein > 150 mg/l within 72 h after admission, necrosis on computed tomography and need for treatment in the intensive care unit. Results: 185 (22%) of patients with acute pancreatitis fulfilled the criteria for SAP. 175 patients were included, mean age 61 +/- 17 years. Hospital stay was in median 13 days. Forty-six... (More)
- Background/Aims: Severe acute pancreatitis ( SAP) is associated with a high morbidity and mortality. The aim was to evaluate treatment, risk factors and outcome in SAP in a centre with a restrictive attitude to surgery. Methods: All cases of acute pancreatitis admitted 1994 - 2003 were analysed retrospectively. SAP was defined as organ failure and/or hospital stay > 7 days together with one or more of: C-reactive protein > 150 mg/l within 72 h after admission, necrosis on computed tomography and need for treatment in the intensive care unit. Results: 185 (22%) of patients with acute pancreatitis fulfilled the criteria for SAP. 175 patients were included, mean age 61 +/- 17 years. Hospital stay was in median 13 days. Forty-six patients had some surgical intervention, in 14 cases directed at the pancreas (8%). Hospital mortality was 9% (n = 16), in 88% ( n = 14) associated with multiple organ dysfunction and 50% ( n = 8) of the deaths occurred within the first week after admission. Of the parameters registered on admission, age and hypotension (systolic blood pressure < 100 mm Hg) were identified as risk factors for death. Conclusion: The present treatment regime for SAP as defined above resulted in a 9% mortality rate, with age and hypotension at admission as predictive factors for death. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/163217
- author
- Andersson, Bodil
LU
; Olin, Hanna
; Eckerwall, Gunilla
LU
and Andersson, Roland
LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Pancreatology
- volume
- 6
- issue
- 6
- pages
- 536 - 541
- publisher
- Karger
- external identifiers
-
- wos:000244258100009
- scopus:33847616553
- ISSN
- 1424-3903
- DOI
- 10.1159/000096977
- language
- English
- LU publication?
- yes
- id
- 4bafb448-8a5e-4fba-93dd-8b1fe01f29e8 (old id 163217)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17106218&dopt=Abstract
- date added to LUP
- 2016-04-01 12:32:18
- date last changed
- 2022-01-27 06:27:30
@article{4bafb448-8a5e-4fba-93dd-8b1fe01f29e8,
abstract = {{Background/Aims: Severe acute pancreatitis ( SAP) is associated with a high morbidity and mortality. The aim was to evaluate treatment, risk factors and outcome in SAP in a centre with a restrictive attitude to surgery. Methods: All cases of acute pancreatitis admitted 1994 - 2003 were analysed retrospectively. SAP was defined as organ failure and/or hospital stay > 7 days together with one or more of: C-reactive protein > 150 mg/l within 72 h after admission, necrosis on computed tomography and need for treatment in the intensive care unit. Results: 185 (22%) of patients with acute pancreatitis fulfilled the criteria for SAP. 175 patients were included, mean age 61 +/- 17 years. Hospital stay was in median 13 days. Forty-six patients had some surgical intervention, in 14 cases directed at the pancreas (8%). Hospital mortality was 9% (n = 16), in 88% ( n = 14) associated with multiple organ dysfunction and 50% ( n = 8) of the deaths occurred within the first week after admission. Of the parameters registered on admission, age and hypotension (systolic blood pressure < 100 mm Hg) were identified as risk factors for death. Conclusion: The present treatment regime for SAP as defined above resulted in a 9% mortality rate, with age and hypotension at admission as predictive factors for death.}},
author = {{Andersson, Bodil and Olin, Hanna and Eckerwall, Gunilla and Andersson, Roland}},
issn = {{1424-3903}},
language = {{eng}},
number = {{6}},
pages = {{536--541}},
publisher = {{Karger}},
series = {{Pancreatology}},
title = {{Severe Acute Pancreatitis - Outcome following a Primarily Non-Surgical Regime.}},
url = {{http://dx.doi.org/10.1159/000096977}},
doi = {{10.1159/000096977}},
volume = {{6}},
year = {{2006}},
}