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Severe Acute Pancreatitis - Outcome following a Primarily Non-Surgical Regime.

Andersson, Bodil LU ; Olin, Hanna; Eckerwall, Gunilla LU and Andersson, Roland LU (2006) In Pancreatology 6(6). p.536-541
Abstract
Background/Aims: Severe acute pancreatitis ( SAP) is associated with a high morbidity and mortality. The aim was to evaluate treatment, risk factors and outcome in SAP in a centre with a restrictive attitude to surgery. Methods: All cases of acute pancreatitis admitted 1994 - 2003 were analysed retrospectively. SAP was defined as organ failure and/or hospital stay > 7 days together with one or more of: C-reactive protein > 150 mg/l within 72 h after admission, necrosis on computed tomography and need for treatment in the intensive care unit. Results: 185 (22%) of patients with acute pancreatitis fulfilled the criteria for SAP. 175 patients were included, mean age 61 +/- 17 years. Hospital stay was in median 13 days. Forty-six... (More)
Background/Aims: Severe acute pancreatitis ( SAP) is associated with a high morbidity and mortality. The aim was to evaluate treatment, risk factors and outcome in SAP in a centre with a restrictive attitude to surgery. Methods: All cases of acute pancreatitis admitted 1994 - 2003 were analysed retrospectively. SAP was defined as organ failure and/or hospital stay > 7 days together with one or more of: C-reactive protein > 150 mg/l within 72 h after admission, necrosis on computed tomography and need for treatment in the intensive care unit. Results: 185 (22%) of patients with acute pancreatitis fulfilled the criteria for SAP. 175 patients were included, mean age 61 +/- 17 years. Hospital stay was in median 13 days. Forty-six patients had some surgical intervention, in 14 cases directed at the pancreas (8%). Hospital mortality was 9% (n = 16), in 88% ( n = 14) associated with multiple organ dysfunction and 50% ( n = 8) of the deaths occurred within the first week after admission. Of the parameters registered on admission, age and hypotension (systolic blood pressure < 100 mm Hg) were identified as risk factors for death. Conclusion: The present treatment regime for SAP as defined above resulted in a 9% mortality rate, with age and hypotension at admission as predictive factors for death. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pancreatology
volume
6
issue
6
pages
536 - 541
publisher
Karger
external identifiers
  • wos:000244258100009
  • scopus:33847616553
ISSN
1424-3903
DOI
10.1159/000096977
language
English
LU publication?
yes
id
4bafb448-8a5e-4fba-93dd-8b1fe01f29e8 (old id 163217)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17106218&dopt=Abstract
date added to LUP
2007-07-20 14:35:04
date last changed
2019-02-20 04:45:36
@article{4bafb448-8a5e-4fba-93dd-8b1fe01f29e8,
  abstract     = {Background/Aims: Severe acute pancreatitis ( SAP) is associated with a high morbidity and mortality. The aim was to evaluate treatment, risk factors and outcome in SAP in a centre with a restrictive attitude to surgery. Methods: All cases of acute pancreatitis admitted 1994 - 2003 were analysed retrospectively. SAP was defined as organ failure and/or hospital stay &gt; 7 days together with one or more of: C-reactive protein &gt; 150 mg/l within 72 h after admission, necrosis on computed tomography and need for treatment in the intensive care unit. Results: 185 (22%) of patients with acute pancreatitis fulfilled the criteria for SAP. 175 patients were included, mean age 61 +/- 17 years. Hospital stay was in median 13 days. Forty-six patients had some surgical intervention, in 14 cases directed at the pancreas (8%). Hospital mortality was 9% (n = 16), in 88% ( n = 14) associated with multiple organ dysfunction and 50% ( n = 8) of the deaths occurred within the first week after admission. Of the parameters registered on admission, age and hypotension (systolic blood pressure &lt; 100 mm Hg) were identified as risk factors for death. Conclusion: The present treatment regime for SAP as defined above resulted in a 9% mortality rate, with age and hypotension at admission as predictive factors for death.},
  author       = {Andersson, Bodil and Olin, Hanna and Eckerwall, Gunilla and Andersson, Roland},
  issn         = {1424-3903},
  language     = {eng},
  number       = {6},
  pages        = {536--541},
  publisher    = {Karger},
  series       = {Pancreatology},
  title        = {Severe Acute Pancreatitis - Outcome following a Primarily Non-Surgical Regime.},
  url          = {http://dx.doi.org/10.1159/000096977},
  volume       = {6},
  year         = {2006},
}