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Reply to letter by Deng et al. "Could the levels of inflammation biomarkers predict OA? : Comment on the article by Roemer FW et al."

Roemer, Frank W LU ; Englund, Martin LU ; Turkiewicz, Aleksandra LU ; Struglics, André LU ; Guermazi, Ali; Lohmander, L Stefan LU ; Larsson, Staffan LU and Frobell, Richard LU (2019) In Arthritis & Rheumatology2013-01-01+01:00
Abstract

As explained in the methods-section, we chose to analyze the 2-year data in regard to inflammatory activity based on MRI and synovial biomarkers (and not earlier time points) as our aim was to capture patients that experienced "prolonged" or chronic inflammation, which may be regarded as a potential risk factor for osteoarthritis (OA) development. Virtually all patients of an acute injury cohort (like the KANON patients) will exhibit acute post-traumatic inflammation in their injured knee to a various extent as manifested by marked changes on imaging (i.e. effusion, traumatic synovitis and haemarthrosis) or in biochemical parameters. This article is protected by copyright. All rights reserved.

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author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
in
Arthritis & Rheumatology2013-01-01+01:00
publisher
John Wiley & Sons
ISSN
1529-0131
DOI
10.1002/art.40936
language
English
LU publication?
yes
id
4d709001-9bf0-4db6-b3de-d13efe1d4eac
date added to LUP
2019-05-27 15:51:10
date last changed
2019-05-28 11:40:35
@article{4d709001-9bf0-4db6-b3de-d13efe1d4eac,
  abstract     = {<p>As explained in the methods-section, we chose to analyze the 2-year data in regard to inflammatory activity based on MRI and synovial biomarkers (and not earlier time points) as our aim was to capture patients that experienced "prolonged" or chronic inflammation, which may be regarded as a potential risk factor for osteoarthritis (OA) development. Virtually all patients of an acute injury cohort (like the KANON patients) will exhibit acute post-traumatic inflammation in their injured knee to a various extent as manifested by marked changes on imaging (i.e. effusion, traumatic synovitis and haemarthrosis) or in biochemical parameters. This article is protected by copyright. All rights reserved.</p>},
  author       = {Roemer, Frank W and Englund, Martin and Turkiewicz, Aleksandra and Struglics, André and Guermazi, Ali and Lohmander, L Stefan and Larsson, Staffan and Frobell, Richard},
  issn         = {1529-0131},
  language     = {eng},
  month        = {05},
  publisher    = {John Wiley & Sons},
  series       = {Arthritis & Rheumatology2013-01-01+01:00},
  title        = {Reply to letter by Deng et al. "Could the levels of inflammation biomarkers predict OA? : Comment on the article by Roemer FW et al."},
  url          = {http://dx.doi.org/10.1002/art.40936},
  year         = {2019},
}