Advanced

Photocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.

T-Khani, Poya LU ; de la Torre, Carolina; Canals, Francesc; Bennet, Hedvig LU ; Simo, Rafael; Hernandez, Cristina; Fex, Malin LU ; Agardh, Carl-David LU ; Hansson, Ola LU and Agardh, Elisabet LU (2015) In Acta Ophthalmologica 93(4). p.348-354
Abstract
Despite the extensive use of retinal photocoagulation for ischaemia and vascular leakage in retinal vascular disease, the molecular mechanisms behind its clinical beneficial effects are still poorly understood. One important target of laser irradiation is the retinal pigment epithelium (RPE). In this study, we aimed at identifying the isolated effects of photocoagulation of RPE at both the mRNA and protein expression levels.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Ophthalmologica
volume
93
issue
4
pages
348 - 354
publisher
Wiley-Blackwell
external identifiers
  • pmid:25604382
  • wos:000354635300032
  • scopus:84929510888
ISSN
1755-3768
DOI
10.1111/aos.12649
language
English
LU publication?
yes
id
2fb42d7d-f89e-4713-8d2e-ada042500fc6 (old id 5040105)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25604382?dopt=Abstract
date added to LUP
2015-02-03 19:57:30
date last changed
2017-06-11 03:16:29
@article{2fb42d7d-f89e-4713-8d2e-ada042500fc6,
  abstract     = {Despite the extensive use of retinal photocoagulation for ischaemia and vascular leakage in retinal vascular disease, the molecular mechanisms behind its clinical beneficial effects are still poorly understood. One important target of laser irradiation is the retinal pigment epithelium (RPE). In this study, we aimed at identifying the isolated effects of photocoagulation of RPE at both the mRNA and protein expression levels.},
  author       = {T-Khani, Poya and de la Torre, Carolina and Canals, Francesc and Bennet, Hedvig and Simo, Rafael and Hernandez, Cristina and Fex, Malin and Agardh, Carl-David and Hansson, Ola and Agardh, Elisabet},
  issn         = {1755-3768},
  language     = {eng},
  number       = {4},
  pages        = {348--354},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Ophthalmologica},
  title        = {Photocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.},
  url          = {http://dx.doi.org/10.1111/aos.12649},
  volume       = {93},
  year         = {2015},
}