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Contribution of diet to the composition of the human gut microbiota.

Graf, Daniela; Di Cagno, Raffaella; Fåk, Frida LU ; Flint, Harry J; Nyman, Margareta LU ; Saarela, Maria and Watzl, Bernhard (2015) In Microbial Ecology in Health and Disease 26.
Abstract
In the human gut, millions of bacteria contribute to the microbiota, whose composition is specific for every individual. Although we are just at the very beginning of understanding the microbiota concept, we already know that the composition of the microbiota has a profound impact on human health. A key factor in determining gut microbiota composition is diet. Preliminary evidence suggests that dietary patterns are associated with distinct combinations of bacteria in the intestine, also called enterotypes. Western diets result in significantly different microbiota compositions than traditional diets. It is currently unknown which food constituents specifically promote growth and functionality of beneficial bacteria in the intestine. The... (More)
In the human gut, millions of bacteria contribute to the microbiota, whose composition is specific for every individual. Although we are just at the very beginning of understanding the microbiota concept, we already know that the composition of the microbiota has a profound impact on human health. A key factor in determining gut microbiota composition is diet. Preliminary evidence suggests that dietary patterns are associated with distinct combinations of bacteria in the intestine, also called enterotypes. Western diets result in significantly different microbiota compositions than traditional diets. It is currently unknown which food constituents specifically promote growth and functionality of beneficial bacteria in the intestine. The aim of this review is to summarize the recently published evidence from human in vivo studies on the gut microbiota-modulating effects of diet. It includes sections on dietary patterns (e.g. Western diet), whole foods, food constituents, as wells as food-associated microbes and their influence on the composition of human gut microbiota. The conclusions highlight the problems faced by scientists in this fast-developing field of research, and the need for high-quality, large-scale human dietary intervention studies. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Microbial Ecology in Health and Disease
volume
26
publisher
Taylor & Francis
external identifiers
  • pmid:25656825
ISSN
0891-060X
DOI
10.3402/mehd.v26.26164
language
English
LU publication?
yes
id
d63f226b-e0f4-4aa9-b7fe-7faa892eeea1 (old id 5145302)
date added to LUP
2015-03-09 17:08:30
date last changed
2016-04-15 16:36:48
@article{d63f226b-e0f4-4aa9-b7fe-7faa892eeea1,
  abstract     = {In the human gut, millions of bacteria contribute to the microbiota, whose composition is specific for every individual. Although we are just at the very beginning of understanding the microbiota concept, we already know that the composition of the microbiota has a profound impact on human health. A key factor in determining gut microbiota composition is diet. Preliminary evidence suggests that dietary patterns are associated with distinct combinations of bacteria in the intestine, also called enterotypes. Western diets result in significantly different microbiota compositions than traditional diets. It is currently unknown which food constituents specifically promote growth and functionality of beneficial bacteria in the intestine. The aim of this review is to summarize the recently published evidence from human in vivo studies on the gut microbiota-modulating effects of diet. It includes sections on dietary patterns (e.g. Western diet), whole foods, food constituents, as wells as food-associated microbes and their influence on the composition of human gut microbiota. The conclusions highlight the problems faced by scientists in this fast-developing field of research, and the need for high-quality, large-scale human dietary intervention studies.},
  articleno    = {26164},
  author       = {Graf, Daniela and Di Cagno, Raffaella and Fåk, Frida and Flint, Harry J and Nyman, Margareta and Saarela, Maria and Watzl, Bernhard},
  issn         = {0891-060X},
  language     = {eng},
  publisher    = {Taylor & Francis},
  series       = {Microbial Ecology in Health and Disease},
  title        = {Contribution of diet to the composition of the human gut microbiota.},
  url          = {http://dx.doi.org/10.3402/mehd.v26.26164},
  volume       = {26},
  year         = {2015},
}