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RIFM fragrance ingredient safety assessment, ethyl anthranilate, CAS registry number 87-25-2.

Api, A M; Belsito, D; Bhatia, S; Bruze, Magnus LU ; Calow, P; Dagli, M L; Dekant, W; Fryer, A D; Kromidas, L and Cava, S LA, et al. (2015) In Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Abstract
The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Reproductive toxicity was based on the Threshold of Toxicological Concern (TTC) of 0.009 mg/kg/day for a Cramer Class II material. The estimated systemic exposure is determined to be below this value assuming 100% absorption from skin contact and inhalation. A systemic exposure below this TTC value is acceptable.
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
publisher
Elsevier
external identifiers
  • pmid:25818467
  • scopus:84934439738
ISSN
1873-6351
DOI
10.1016/j.fct.2015.03.017
language
English
LU publication?
yes
id
e91ffe67-27dc-4cab-b001-13e7cb3ea1ec (old id 5257412)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25818467?dopt=Abstract
date added to LUP
2015-04-04 16:47:23
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2017-01-22 04:19:20
@article{e91ffe67-27dc-4cab-b001-13e7cb3ea1ec,
  abstract     = {The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Reproductive toxicity was based on the Threshold of Toxicological Concern (TTC) of 0.009 mg/kg/day for a Cramer Class II material. The estimated systemic exposure is determined to be below this value assuming 100% absorption from skin contact and inhalation. A systemic exposure below this TTC value is acceptable.},
  author       = {Api, A M and Belsito, D and Bhatia, S and Bruze, Magnus and Calow, P and Dagli, M L and Dekant, W and Fryer, A D and Kromidas, L and Cava, S LA and Lalko, J F and Lapczynski, A and Liebler, D C and Miyachi, Y and Politano, V T and Ritacco, G and Salvito, D and Shen, J and Schultz, T W and Sipes, I G and Wall, B and Wilcox, D K},
  issn         = {1873-6351},
  language     = {eng},
  month        = {03},
  publisher    = {Elsevier},
  series       = {Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  title        = {RIFM fragrance ingredient safety assessment, ethyl anthranilate, CAS registry number 87-25-2.},
  url          = {http://dx.doi.org/10.1016/j.fct.2015.03.017},
  year         = {2015},
}