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Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.

Asciutto, Giuseppe LU ; Dias, Nuno LU ; Edsfeldt, Andreas LU ; Nitulescu, Mihaela LU ; Persson, Ana LU ; Nilsson, Marie MN LU ; Dunér, Pontus LU ; Nilsson, Jan LU and Goncalves, Isabel LU (2015) In PLoS ONE 10(3).
Abstract
Atherosclerotic plaques with a low content of connective tissue proteins are believed to have an increased risk of rupture and to give rise to clinical events. The aim of the present study was to investigate if the content of elastin, collagen and of the matrix metalloproteinase (MMP) -1, -3, -9 and -12 in plaques removed at surgery can be associated with the occurrence of ipsilateral symptoms.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
10
issue
3
publisher
Public Library of Science
external identifiers
  • pmid:25803692
  • wos:000353889600122
  • scopus:84925862816
ISSN
1932-6203
DOI
10.1371/journal.pone.0121086
language
English
LU publication?
yes
id
fb1984c1-fd54-452e-8d1b-28fd760ff95f (old id 5257709)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25803692?dopt=Abstract
date added to LUP
2015-04-04 18:03:05
date last changed
2017-02-05 04:07:00
@article{fb1984c1-fd54-452e-8d1b-28fd760ff95f,
  abstract     = {Atherosclerotic plaques with a low content of connective tissue proteins are believed to have an increased risk of rupture and to give rise to clinical events. The aim of the present study was to investigate if the content of elastin, collagen and of the matrix metalloproteinase (MMP) -1, -3, -9 and -12 in plaques removed at surgery can be associated with the occurrence of ipsilateral symptoms.},
  articleno    = {e0121086},
  author       = {Asciutto, Giuseppe and Dias, Nuno and Edsfeldt, Andreas and Nitulescu, Mihaela and Persson, Ana and Nilsson, Marie MN and Dunér, Pontus and Nilsson, Jan and Goncalves, Isabel},
  issn         = {1932-6203},
  language     = {eng},
  number       = {3},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0121086},
  volume       = {10},
  year         = {2015},
}