Auditory event-related potentials are related to cognition at preschool age after preterm birth
Hövel, Holger LU ; Partanen, E ; Tideman, Eva LU ; Stjernqvist, Karin LU ; Hellström-Westas, Lena LU ; Houtilainen, M and Fellman, Vineta LU
(2015)
In Pediatric Research
77(4).
p.570-578
- Abstract
- Background:Auditory event-related potentials (AERP) are neurophysiological correlates of sound perception and cognitive processes. Our aim was to study in very preterm born children at preschool age if AERP correlate with cognitive outcome.Methods:Seventy children (mean ± SD gestational age 27.4 ± 1.9 wk, birth weight 996 ± 288 g) were investigated at age 4.3-5.3 y with psychological testing (WPPSI-R, four subtests of NEPSY). Electroencephalogram was recorded while they listened to a repeated standard tone, randomly replaced by one of three deviants. Latencies and amplitudes for AERP components and mean amplitudes in successive 50-ms AERP time windows were measured.Results:Better cognitive test results and higher gestational age correlated... (More)
- Background:Auditory event-related potentials (AERP) are neurophysiological correlates of sound perception and cognitive processes. Our aim was to study in very preterm born children at preschool age if AERP correlate with cognitive outcome.Methods:Seventy children (mean ± SD gestational age 27.4 ± 1.9 wk, birth weight 996 ± 288 g) were investigated at age 4.3-5.3 y with psychological testing (WPPSI-R, four subtests of NEPSY). Electroencephalogram was recorded while they listened to a repeated standard tone, randomly replaced by one of three deviants. Latencies and amplitudes for AERP components and mean amplitudes in successive 50-ms AERP time windows were measured.Results:Better cognitive test results and higher gestational age correlated with shorter P1 latencies and more positive mean amplitudes 150-500 ms after stimulus change onset. Neonatal brain damage was associated with a negative displacement of AERP curves. Neonatal morbidity had an impact on earlier time windows while gestational age and brain damage on both early and later time windows.Conclusion:AERP measures were associated with cognitive outcome. Neonatal morbidity mainly affects early cortical auditory encoding, while immaturity and brain damage additionally influence higher cortical functions of auditory perception and distraction. Perinatal auditory environment might play a role in development of auditory processing.Pediatric Research (2015); doi:10.1038/pr.2015.7. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5158405
- author
- Hövel, Holger
LU
; Partanen, E
; Tideman, Eva
LU
; Stjernqvist, Karin
LU
; Hellström-Westas, Lena
LU
; Houtilainen, M
and Fellman, Vineta
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Pediatric Research
- volume
- 77
- issue
- 4
- pages
- 570 - 578
- publisher
- International Pediatric Foundation Inc.
- external identifiers
-
- scopus:84924976085
- pmid:25642663
- wos:000351335600011
- pmid:25642663
- ISSN
- 1530-0447
- DOI
- 10.1038/pr.2015.7
- language
- English
- LU publication?
- yes
- id
- 53c13319-0873-4024-99e7-cf8c4201f917 (old id 5158405)
- date added to LUP
- 2016-04-01 10:46:31
- date last changed
- 2022-04-28 01:17:45
@article{53c13319-0873-4024-99e7-cf8c4201f917,
abstract = {{Background:Auditory event-related potentials (AERP) are neurophysiological correlates of sound perception and cognitive processes. Our aim was to study in very preterm born children at preschool age if AERP correlate with cognitive outcome.Methods:Seventy children (mean ± SD gestational age 27.4 ± 1.9 wk, birth weight 996 ± 288 g) were investigated at age 4.3-5.3 y with psychological testing (WPPSI-R, four subtests of NEPSY). Electroencephalogram was recorded while they listened to a repeated standard tone, randomly replaced by one of three deviants. Latencies and amplitudes for AERP components and mean amplitudes in successive 50-ms AERP time windows were measured.Results:Better cognitive test results and higher gestational age correlated with shorter P1 latencies and more positive mean amplitudes 150-500 ms after stimulus change onset. Neonatal brain damage was associated with a negative displacement of AERP curves. Neonatal morbidity had an impact on earlier time windows while gestational age and brain damage on both early and later time windows.Conclusion:AERP measures were associated with cognitive outcome. Neonatal morbidity mainly affects early cortical auditory encoding, while immaturity and brain damage additionally influence higher cortical functions of auditory perception and distraction. Perinatal auditory environment might play a role in development of auditory processing.Pediatric Research (2015); doi:10.1038/pr.2015.7.}},
author = {{Hövel, Holger and Partanen, E and Tideman, Eva and Stjernqvist, Karin and Hellström-Westas, Lena and Houtilainen, M and Fellman, Vineta}},
issn = {{1530-0447}},
language = {{eng}},
number = {{4}},
pages = {{570--578}},
publisher = {{International Pediatric Foundation Inc.}},
series = {{Pediatric Research}},
title = {{Auditory event-related potentials are related to cognition at preschool age after preterm birth}},
url = {{http://dx.doi.org/10.1038/pr.2015.7}},
doi = {{10.1038/pr.2015.7}},
volume = {{77}},
year = {{2015}},
}